Overview

  • Product name

    Anti-TAS2R8 antibody
  • Description

    Rabbit polyclonal to TAS2R8
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from internal sequence of human TAS2R8

  • Positive control

    • Extracts from COLO cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab75109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 36 kDa.
ELISA 1/10000.

Target

  • Relevance

    TAS2R8 is a receptor that may play a role in the perception of bitterness and is gustducin-linked. It may play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
  • Cellular localization

    Membrane; Multipass membrane protein.
  • Database links

  • Alternative names

    • T2R8 antibody
    • Taste receptor, family B, member 5 antibody
    • Taste receptor, type 2, member 8 antibody
    • TRB5 antibody

Images

  • All lanes : Anti-TAS2R8 antibody (ab75109) at 1/500 dilution

    Lane 1 : Extracts from COLO cells
    Lane 2 : Extracts from COLO cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 36 kDa
    Observed band size: 36 kDa
    Additional bands at: 25 kDa. We are unsure as to the identity of these extra bands.

References

This product has been referenced in:

  • Kohanski MA  et al. Solitary chemosensory cells are a primary epithelial source of IL-25 in patients with chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol N/A:N/A (2018). Read more (PubMed: 29778504) »
See 1 Publication for this product

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