Anti-Tau antibody [TAU-5] - BSA and Azide free (ab80579)

Mouse monoclonal Tau antibody [TAU-5]. Validated in WB, IP, ELISA, Flow Cyt, ICC/IF and tested in Mouse, Rat, Sheep, Cow, Human. Cited in 39 publication(s). Independently reviewed in 5 review(s).

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ab80579 has been referenced in 43 publications.

  • Huang R  et al. Increased Ratio of Global O-GlcNAcylation to Tau Phosphorylation at Thr212 Site Is Associated With Better Memory Function in Patients With Type 2 Diabetes. Front Physiol 10:110 (2019). PubMed: 30837891
  • Silva MC  et al. Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. Elife 8:N/A (2019). PubMed: 30907729
  • Zhang Y  et al. a-lipoic acid attenuates spatial learning and memory impairment induced by hepatectomy. Exp Ther Med 17:2329-2333 (2019). PubMed: 30867718
  • Mahaman YAR  et al. Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments. J Alzheimers Dis 63:1141-1159 (2018). PubMed: 29710724
  • Fang YY  et al. Evidence of altered depression and dementia-related proteins in the brains of young rats after ovariectomy. J Neurochem 146:703-721 (2018). PubMed: 29939407
  • Ritter ML  et al. Frontotemporal Dementia-Associated N279K Tau Mutation Localizes at the Nuclear Compartment. Front Cell Neurosci 12:202 (2018). PubMed: 30050413
  • Ahmad W Dihydrolipoamide dehydrogenase suppression induces human tau phosphorylation by increasing whole body glucose levels in a C. elegans model of Alzheimer's Disease. Exp Brain Res N/A:N/A (2018). PubMed: 30056470
  • Pu D  et al. Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity. Neuroscience 381:35-45 (2018). WB ; Mouse . PubMed: 29684505
  • Rousseaux MW  et al. Depleting Trim28 in adult mice is well tolerated and reduces levels of a-synuclein and tau. Elife 7:N/A (2018). PubMed: 29863470
  • Zhu Y  et al. Chronic Sleep Disruption Advances the Temporal Progression of Tauopathy in P301S Mutant Mice. J Neurosci 38:10255-10270 (2018). PubMed: 30322903
  • Li Y  et al. ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM. Front Cell Neurosci 12:489 (2018). PubMed: 30618636
  • Zhang X  et al. RNA stores tau reversibly in complex coacervates. PLoS Biol 15:e2002183 (2017). WB . PubMed: 28683104
  • Wang YC  et al. Post-acute delivery of memantine promotes post-ischemic neurological recovery, peri-infarct tissue remodeling, and contralesional brain plasticity. J Cereb Blood Flow Metab 37:980-993 (2017). PubMed: 27170698
  • Xu W  et al. Capsaicin reduces Alzheimer-associated tau changes in the hippocampus of type 2 diabetes rats. PLoS One 12:e0172477 (2017). PubMed: 28225806
  • Lombardi LM  et al. An RNA interference screen identifies druggable regulators of MeCP2 stability. Sci Transl Med 9:N/A (2017). PubMed: 28835516
  • Di Primio C  et al. The Distance between N and C Termini of Tau and of FTDP-17 Mutants Is Modulated by Microtubule Interactions in Living Cells. Front Mol Neurosci 10:210 (2017). PubMed: 28713242
  • Bou Samra E  et al. A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival. Nat Commun 8:693 (2017). PubMed: 28947735
  • Yang Y  et al. Fuzheng Quxie Decoction Ameliorates Learning and Memory Impairment in SAMP8 Mice by Decreasing Tau Hyperphosphorylation. Evid Based Complement Alternat Med 2017:5934254 (2017). PubMed: 29422936
  • Ercan E  et al. A validated antibody panel for the characterization of tau post-translational modifications. Mol Neurodegener 12:87 (2017). PubMed: 29157277
  • Yadirgi G  et al. Immuno-detection of cleaved SNAP-25 from differentiated mouse embryonic stem cells provides a sensitive assay for determination of botulinum A toxin and antitoxin potency. J Immunol Methods 451:90-99 (2017). ICC/IF . PubMed: 28943257
  • Loss O & Stephenson FA Developmental changes in trak-mediated mitochondrial transport in neurons. Mol Cell Neurosci 80:134-147 (2017). Rat . PubMed: 28300646
  • Huang CJ  et al. Detection of lower levels of SNAP25 using multiple microarray systems and its functional significance in medulloblastoma. Int J Mol Med 39:1195-1205 (2017). IF ; Human . PubMed: 28339008
  • Allison R  et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol 216:1337-1355 (2017). IF ; Human . PubMed: 28389476
  • Zeng WB  et al. Anterograde monosynaptic transneuronal tracers derived from herpes simplex virus 1 strain H129. Mol Neurodegener 12:38 (2017). ICC/IF ; Mouse . PubMed: 28499404
  • Ayyadevara S  et al. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. Aging Cell 15:924-39 (2016). IHC-P, IP ; Human . PubMed: 27448508
  • Cartagena CM  et al. Subacute Changes in Cleavage Processing of Amyloid Precursor Protein and Tau following Penetrating Traumatic Brain Injury. PLoS One 11:e0158576 (2016). WB ; Mouse . PubMed: 27428544
  • Cheng YC  et al. Knocking down of heat-shock protein 27 directs differentiation of functional glutamatergic neurons from placenta-derived multipotent cells. Sci Rep 6:30314 (2016). ICC/IF ; Human . PubMed: 27444754
  • Sadick JS  et al. Protein characterization of intracellular target-sorted, formalin-fixed cell subpopulations. Sci Rep 6:33999 (2016). WB, ICC/IF ; Human . PubMed: 27666089
  • Wilson GN  et al. Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma. Front Neurosci 10:494 (2016). IP ; Mouse . PubMed: 27857681
  • Connell JW  et al. Quantitative Gait Analysis Using a Motorized Treadmill System Sensitively Detects Motor Abnormalities in Mice Expressing ATPase Defective Spastin. PLoS One 11:e0152413 (2016). Mouse . PubMed: 27019090
  • Chauhan S  et al. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nat Commun 6:8620 (2015). ICC/IF ; Mouse . PubMed: 26503418
  • Jiao SS  et al. Edaravone alleviates Alzheimer's disease-type pathologies and cognitive deficits. Proc Natl Acad Sci U S A 112:5225-30 (2015). WB . PubMed: 25847999
  • Mikhail F  et al. Lack of exacerbation of neurodegeneration in a double transgenic mouse model of mutant LRRK2 and tau. Hum Mol Genet 24:3545-56 (2015). WB ; Mouse . PubMed: 25804954
  • Min SW  et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nat Med 21:1154-62 (2015). IP . PubMed: 26390242
  • Das V  et al. Effect of taxoid and nontaxoid site microtubule-stabilizing agents on axonal transport of mitochondria in untransfected and ECFP-htau40-transfected rat cortical neurons in culture. J Neurosci Res 92:1155-66 (2014). Rat . PubMed: 24788108
  • Tan MS  et al. IL12/23 p40 inhibition ameliorates Alzheimer's disease-associated neuropathology and spatial memory in SAMP8 mice. J Alzheimers Dis 38:633-46 (2014). WB ; Mouse . PubMed: 24047617
  • Richens JL  et al. Practical detection of a definitive biomarker panel for Alzheimer's disease; comparisons between matched plasma and cerebrospinal fluid. Int J Mol Epidemiol Genet 5:53-70 (2014). ELISA ; Human . PubMed: 24959311
  • Zhang X  et al. Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models. J Biol Chem 288:22042-56 (2013). PubMed: 23737518
  • Das V & Miller JH Non-taxoid site microtubule-stabilizing drugs work independently of tau overexpression in mouse N2a neuroblastoma cells. Brain Res 1489:121-32 (2012). WB . PubMed: 23085090
  • van Abel D  et al. STOX1A induces phosphorylation of tau proteins at epitopes hyperphosphorylated in Alzheimer's disease. Neurosci Lett 528:104-9 (2012). WB . PubMed: 22995177
  • Oz S  et al. The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activities. PLoS One 7:e51458 (2012). Mouse . PubMed: 23272107
  • Yang M  et al. Precursor of Brain-derived Neurotrophic Factor (proBDNF) Forms a Complex with Huntingtin-associated Protein-1 (HAP1) and Sortilin That Modulates proBDNF Trafficking, Degradation, and Processing. J Biol Chem 286:16272-84 (2011). ICC/IF ; Mouse . PubMed: 21357693
  • Allyson J  et al. Blockade of NR2A-containing NMDA receptors induces Tau phosphorylation in rat hippocampal slices. Neural Plast 2010:340168 (2010). WB ; Rat . PubMed: 20508838

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