Tazobactam sodium salt, beta-lactamase inhibitor (ab143702)

Overview

  • Product name

    Tazobactam sodium salt, beta-lactamase inhibitor
  • Description

    β-lactamase inhibitor. Antibiotic agent.
  • Biological description

    β-lactamase inhibitor. Antibiotic agent. Penicillin derivative. Broadens the spectrum of activity of piperacillin (ab143438) in vivo.
  • Purity

    > 99%
  • CAS Number

    89785-84-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide sodium salt
  • Molecular weight

    322.27
  • Molecular formula

    C10H11N4NaO5S
  • PubChem identifier

    23663400
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Ghiselli R  et al. Protective effect of citropin 1.1 and tazobactam-piperacillin against oxidative damage and lethality in mice models of gram-negative sepsis. J Surg Res 171:726-33 (2011). Read more (PubMed: 20605608) »
  • Cirioni O  et al. Tachyplesin III and granulocyte-colony stimulating factor enhance the efficacy of tazobactam/piperacillin in a neutropenic mouse model of polymicrobial peritonitis. Peptides 29:31-8 (2008). Read more (PubMed: 18068869) »
  • Ghiselli R  et al. Efficacy of the bovine antimicrobial peptide indolicidin combined with piperacillin/tazobactam in experimental rat models of polymicrobial peritonitis. Crit Care Med 36:240-5 (2008). Read more (PubMed: 18090372) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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