Key features and details
- Rabbit polyclonal to TBLR1/TBL1XR1
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TBLR1/TBL1XR1 antibody
See all TBLR1/TBL1XR1 primary antibodies
DescriptionRabbit polyclonal to TBLR1/TBL1XR1
Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow, Monkey, Zebrafish
Recombinant fragment corresponding to Human TBLR1/TBL1XR1 aa 210-484.
Database link: NP_078941
- A431 whole cell lysate; Cal27 xenograft; HeLa cells; 293T, H1299, Molt-4 and Raji cell lines
Previously labelled as TBLR1.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Our Abpromise guarantee covers the use of ab97398 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 56 kDa.|
|IHC-P||1/100 - 1/250.|
|ICC/IF||1/100 - 1/200.|
FunctionF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
Sequence similaritiesBelongs to the WD repeat EBI family.
Contains 1 F-box-like domain.
Contains 1 LisH domain.
Contains 8 WD repeats.
DomainThe F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
- Information by UniProt
- C21 antibody
- DC42 antibody
- F box like/WD repeat containing protein TBL1XR1 antibody
Anti-TBLR1/TBL1XR1 antibody (ab97398) at 1/1000 dilution + A431 whole cell lysate at 30 µg
Predicted band size: 56 kDa
ab97398, at 1/100 dilution, staining TBLR1/TBL1XR1 in paraffin-embedded Cal27 xenograft by Immunohistochemistry.
Immunofluorescence analysis of TBLR1/TBL1XR1 in paraformaldehyde-fixed HeLa cells, using ab97398 at 1/200 dilution (top image) and merged with DNA probe (bottom image).
ab97398 has not yet been referenced specifically in any publications.