• Product name

    Anti-Tbp7 antibody [TBP7-27]
    See all Tbp7 primary antibodies
  • Description

    Mouse monoclonal [TBP7-27] to Tbp7
  • Host species

  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Rat, Rabbit, Human
  • Immunogen

    Recombinant full length protein (Human).

  • Positive control

    • Tested with rabbit 26S proteasome preparation.



Our Abpromise guarantee covers the use of ab22634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    ICC/IF: 1/1000 (PMID 18986984).
    WB: 1/1000 - 1/2500. Detects a band of approximately 50 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
    • Sequence similarities

      Belongs to the AAA ATPase family.
    • Cellular localization

      Cytoplasm. Nucleus.
    • Information by UniProt
    • Database links

    • Alternative names

      • 26S protease regulatory subunit 6B antibody
      • 26S proteasome AAA ATPase subunit RPT3 antibody
      • 26S proteasome AAA-ATPase subunit RPT3 antibody
      • MB67 interacting protein antibody
      • MB67-interacting protein antibody
      • MIP224 antibody
      • Protease 26S subunit 6 antibody
      • Proteasome (prosome macropain) 26S subunit ATPase 4 antibody
      • Proteasome 19S S6 antibody
      • Proteasome 26S subunit ATPase 4 antibody
      • Proteasome 26S subunit, ATPase, 4 antibody
      • PRS6B_HUMAN antibody
      • PSMC4 antibody
      • RPT3 antibody
      • S6 antibody
      • Tat binding protein 7 antibody
      • TAT-binding protein 7 antibody
      • TBP 7 antibody
      • TBP-7 antibody
      see all


    • Lane 1 : Anti-Tbp7 antibody [TBP7-27] (ab22634) at 1/1000 dilution (rabbit 26S
      proteasome preparation)
      Lane 2 : Anti-Tbp7 antibody [TBP7-27] (ab22634) at 1/2500 dilution (rabbit 26S
      proteasome preparation)

      All lanes :

      Performed under reducing conditions.

      Observed band size: 50 kDa
      why is the actual band size different from the predicted?

      Exposure time: 1 minute
    • ab22634 staining Tbp7 in mock transfected rat primary neurons by Immunocytochemistry/ Immunofluorescence. Primary cultures of rat hippocampal neurons were prepared from E18 rats. Cells were fixed in 4% paraformaldehyde and incubated with primary antibody at 1/1000 dilution. The image show red staining with ab22634, nucleus was stained blue with Hoechst H33258 and right image show merged images. The green color seen in right image is the GFP staining in similar experiment.


    This product has been referenced in:

    • Wilson CH  et al. Increased expression of peroxiredoxin 1 and identification of a novel lipid-metabolizing enzyme in the early phase of liver ischemia reperfusion injury. Proteomics 11:4385-96 (2011). WB ; Rat . Read more (PubMed: 21905220) »
    • Rousseau E  et al. Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones. J Biol Chem 284:1917-29 (2009). WB, ICC/IF ; Human, Rat . Read more (PubMed: 18986984) »
    See all 2 Publications for this product

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