Product nameAnti-Tbx20 antibody
See all Tbx20 primary antibodies
Species reactivityReacts with: Human
Predicted to work with: Mouse, Chicken, Zebrafish
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
PurityImmunogen affinity purified
|WB||Use at an assay dependent concentration. Predicted molecular weight: 33 kDa.|
FunctionProbable transcriptional regulator involved in developmental processes.
Involvement in diseaseDefects in TBX20 are the cause of atrial septal defect type 4 (ASD4) [MIM:611363]. ASD4 is a congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria. ASD4 patients show other heart abnormalities including defects in septation, chamber growth and valvulogenesis. ASD4 is not associated with defects in the cardiac conduction system or with non-cardiac abnormalities.
Sequence similaritiesContains 1 T-box DNA-binding domain.
- Information by UniProt
- T-box 20 antibody
- T-box protein 20 antibody
- T-box transcription factor TBX20 antibody
Anti-Tbx20 antibody (ab93058) at 1 µg/ml + Human Fetal Heart - Total Protein Tissue Lysate at 10 µg
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 33 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted?
Additional bands at: 120 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 20 minutes
Further characterization on this product is underway. Abcam welcomes customer feedback and would appreciate any comments regarding this product and the data presented above.
This product has been referenced in:
- Caballero R et al. Tbx20 controls the expression of the KCNH2 gene and of hERG channels. Proc Natl Acad Sci U S A 114:E416-E425 (2017). WB . Read more (PubMed: 28049825) »
- Just S et al. Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish. PLoS One 11:e0167306 (2016). WB ; Zebrafish . Read more (PubMed: 27907103) »