Overview

  • Product name

  • Description

    Rabbit polyclonal to TC1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human TC1 aa 209-285.
    Database link: O60779

  • Positive control

    • IHC-P: Human prostate and glioma tissue.
  • General notes

    Protein previously labeled as SLC19A2.

Properties

Applications

Our Abpromise guarantee covers the use of ab238548 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500.

Target

  • Function

    High-affinity transporter for the intake of thiamine.
  • Tissue specificity

    Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung.
  • Involvement in disease

    Thiamine-responsive megaloblastic anemia syndrome
  • Sequence similarities

    Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • S19A2_HUMAN antibody
    • SLC19A2 antibody
    • Solute carrier family 19 member 2 antibody
    • TC1 antibody
    • Thiamine carrier 1 antibody
    • Thiamine transporter 1 antibody
    • THT1 antibody
    • ThTr 1 antibody
    • ThTr-1 antibody
    • ThTr1 antibody
    • TRMA antibody
    see all

Images

  • Paraffin-embedded human prostate tissue stained for TC1 with ab238548 at a 1/300 dilution in immunohistochemical analysis.

    After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 minutes at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • Paraffin-embedded human glioma tissue stained for TC1 with ab238548 at a 1/300 dilution in immunohistochemical analysis.

    After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 minutes at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

References

ab238548 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab238548.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up