Key features and details
- Mouse polyclonal to TC10
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TC10 antibody
See all TC10 primary antibodies
DescriptionMouse polyclonal to TC10
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
- TC10 transfected 293T cell lysate. HeLa cells.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.4
Constituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab168645 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa.|
|ICC/IF||Use a concentration of 10 µg/ml.|
FunctionPlasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
Sequence similaritiesBelongs to the small GTPase superfamily. Rho family.
modificationsMay be post-translationally modified by both palmitoylation and polyisoprenylation.
Cellular localizationCytoplasm. Cell membrane.
- Information by UniProt
- ARHQ antibody
- Ras homolog gene family member Q antibody
- RAS like family 7 member A antibody
All lanes : Anti-TC10 antibody (ab168645) at 1 µg/ml
Lane 1 : TC10 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
All lanes : Goat Anti-Mouse IgG (H&L)-HRP
at 1/2500 dilution
Developed using the ECL technique.
Predicted band size: 23 kDa
Immunofluorescence analysis of HeLa cells, labeling TC10 with ab168645 at 10 µg/ml.
ab168645 has been referenced in 1 publication.
- Mayer S et al. Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission. Proc Natl Acad Sci U S A 110:20795-800 (2013). PubMed: 24297911