Anti-TC10 antibody [Y304] (ab32079)


  • Product name
    Anti-TC10 antibody [Y304]
    See all TC10 primary antibodies
  • Description
    Rabbit monoclonal [Y304] to TC10
  • Host species
  • Specificity
    ab32079 recognises TC10.
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt or IP
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide within Human TC10 aa 100-200. The exact sequence is proprietary.
    (Peptide available as ab186757)

  • Positive control
    • 293 cell lysate, HeLa cells
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.


Associated products


Our Abpromise guarantee covers the use of ab32079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 23 kDa.Can be blocked with TC10 peptide (ab186757).
ICC/IF 1/250 - 1/500.
  • Application notes
    Is unsuitable for Flow Cyt or IP.
  • Target

    • Function
      Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
    • Sequence similarities
      Belongs to the small GTPase superfamily. Rho family.
    • Post-translational
      May be post-translationally modified by both palmitoylation and polyisoprenylation.
    • Cellular localization
      Cytoplasm. Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ARHQ antibody
      • Ras homolog gene family member Q antibody
      • RAS like family 7 member A antibody
      • Ras like protein family member 7A antibody
      • Ras like protein TC10 antibody
      • Ras related GTP binding protein TC10 antibody
      • Ras-like protein family member 7A antibody
      • Ras-like protein TC10 antibody
      • RASL7A antibody
      • Rho related GTP binding protein RhoQ antibody
      • Rho-related GTP-binding protein RhoQ antibody
      • Rhoq antibody
      • RHOQ_HUMAN antibody
      • TC10A antibody
      see all


    • Anti-TC10 antibody [Y304] (ab32079) at 1/1000 dilution + 293 cell lysate

      Predicted band size: 23 kDa
      Observed band size: 25 kDa (why is the actual band size different from the predicted?)

    • Immunofluorescent analysis of TC10 expression in HeLa cells using 1/250 ab 32079.


    This product has been referenced in:
    • Liang J  et al. Inhibition of the mevalonate pathway enhances cancer cell oncolysis mediated by M1 virus. Nat Commun 9:1524 (2018). Read more (PubMed: 29670091) »
    • Fujita A  et al. GTP hydrolysis of TC10 promotes neurite outgrowth through exocytic fusion of Rab11- and L1-containing vesicles by releasing exocyst component Exo70. PLoS One 8:e79689 (2013). ICC/IF . Read more (PubMed: 24223996) »

    See all 5 Publications for this product

    Customer reviews and Q&As

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    Abcam guarantees this product to work in the species/application used in this Abreview.
    Western blot
    Rat Tissue lysate - other (embryonic dorsal root ganglia)
    Loading amount
    30 µg
    embryonic dorsal root ganglia
    Gel Running Conditions
    Reduced Denaturing
    Blocking step
    Odyssey Blocking Buffer as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 50% · Temperature: 25°C

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    Verified customer

    Submitted Nov 03 2010


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