Overview

  • Product name

  • Description

    Rabbit polyclonal to TC21
  • Host species

    Rabbit
  • Specificity

    The immunogen shares 71% homology with RRAS, P10301.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Zebrafish
  • Immunogen

    Recombinant fragment corresponding to Human TC21 aa 1-186 (N terminal).

  • Positive control

    • 293T, A431, H1299, HeLa, HepG2, MOLT4, Raji cells
  • General notes

    Protein previously labeled as RRAS2.

Properties

Applications

Our Abpromise guarantee covers the use of ab96307 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 23 kDa.

Target

  • Function

    It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
  • Tissue specificity

    Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.
  • Involvement in disease

    Ovarian cancer
  • Sequence similarities

    Belongs to the small GTPase superfamily. Ras family.
  • Post-translational
    modifications

    May be post-translationally modified by both palmitoylation and polyisoprenylation.
  • Cellular localization

    Cell membrane. Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
  • Information by UniProt
  • Database links

  • Alternative names

    • C86394 antibody
    • Oncogene RRAS2 antibody
    • Oncogene TC21 antibody
    • Ras like protein TC21 antibody
    • Ras related protein R Ras2 antibody
    • Ras-like protein TC21 antibody
    • Ras-related protein R-Ras2 antibody
    • Related RAS viral (r ras) oncogene homolog 2 antibody
    • Related RAS viral oncogene homolog 2 antibody
    • RRAS 2 antibody
    • RRAS2 antibody
    • RRAS2_HUMAN antibody
    • TC 21 antibody
    • TC21 antibody
    • Teratocarcinoma oncogene antibody
    • Teratocarcinoma oncogene TC21 antibody
    see all

Images

  • Anti-TC21 antibody (ab96307) at 1/5000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size: 23 kDa



    12% SDS PAGE

References

ab96307 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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