Key features and details
- Rabbit polyclonal to TC21
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TC21 antibody
See all TC21 primary antibodies
DescriptionRabbit polyclonal to TC21
SpecificityThe immunogen shares 71% homology with RRAS, P10301.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Zebrafish
Recombinant fragment corresponding to Human TC21 aa 1-186 (N terminal).
- 293T, A431, H1299, HeLa, HepG2, MOLT4, Raji cells
Protein previously labeled as RRAS2.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab96307 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 23 kDa.|
FunctionIt is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
Tissue specificityUbiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.
Involvement in diseaseOvarian cancer
Sequence similaritiesBelongs to the small GTPase superfamily. Ras family.
modificationsMay be post-translationally modified by both palmitoylation and polyisoprenylation.
Cellular localizationCell membrane. Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
- Information by UniProt
- C86394 antibody
- Oncogene RRAS2 antibody
- Oncogene TC21 antibody
ab96307 has not yet been referenced specifically in any publications.