Overview

  • Product name

    Anti-TC21 antibody [EM-50] (Phycoerythrin)
    See all TC21 primary antibodies
  • Description

    Mouse monoclonal [EM-50] to TC21 (Phycoerythrin)
  • Host species

    Mouse
  • Conjugation

    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • Flow Cyt: HEK-293 TC21 transfectants.
  • General notes

    Protein previously labeled as RRAS2.

Properties

Applications

Our Abpromise guarantee covers the use of ab230662 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Target

  • Function

    It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
  • Tissue specificity

    Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.
  • Involvement in disease

    Ovarian cancer
  • Sequence similarities

    Belongs to the small GTPase superfamily. Ras family.
  • Post-translational
    modifications

    May be post-translationally modified by both palmitoylation and polyisoprenylation.
  • Cellular localization

    Cell membrane. Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
  • Information by UniProt
  • Database links

  • Alternative names

    • C86394 antibody
    • Oncogene RRAS2 antibody
    • Oncogene TC21 antibody
    • Ras like protein TC21 antibody
    • Ras related protein R Ras2 antibody
    • Ras-like protein TC21 antibody
    • Ras-related protein R-Ras2 antibody
    • Related RAS viral (r ras) oncogene homolog 2 antibody
    • Related RAS viral oncogene homolog 2 antibody
    • RRAS 2 antibody
    • RRAS2 antibody
    • RRAS2_HUMAN antibody
    • TC 21 antibody
    • TC21 antibody
    • Teratocarcinoma oncogene antibody
    • Teratocarcinoma oncogene TC21 antibody
    see all

Images

  • Flow cytometric analysis of HEK-293 (human epithelial cell line from embryonic kidney) TC21 transfectants labeling TC21 with ab230662 (Red).

References

ab230662 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab230662.
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