Anti-TC21 antibody [EM-50] (Phycoerythrin) (ab230662)

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Overview

  • Product name

    Anti-TC21 antibody [EM-50] (Phycoerythrin)
    See all TC21 primary antibodies

  • Description

    Mouse monoclonal [EM-50] to TC21 (Phycoerythrin)

  • Host species

    Mouse

  • Conjugation

    Phycoerythrin. Ex: 488nm, Em: 575nm

  • Tested applications

    Suitable for: Flow Cytmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • Flow Cyt: HEK-293 TC21 transfectants.

  • General notes

    Protein previously labeled as RRAS2.

Properties

Applications

Our Abpromise guarantee covers the use of ab230662 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Target

  • Function

    It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.

  • Tissue specificity

    Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.

  • Involvement in disease

    Ovarian cancer

  • Sequence similarities

    Belongs to the small GTPase superfamily. Ras family.

  • Post-translational
    modifications

    May be post-translationally modified by both palmitoylation and polyisoprenylation.

  • Cellular localization

    Cell membrane. Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
  • Information by UniProt

  • Database links

    • Alternative names

      • C86394 antibody
      • Oncogene RRAS2 antibody
      • Oncogene TC21 antibody
      • Ras like protein TC21 antibody
      • Ras related protein R Ras2 antibody
      • Ras-like protein TC21 antibody
      • Ras-related protein R-Ras2 antibody
      • Related RAS viral (r ras) oncogene homolog 2 antibody
      • Related RAS viral oncogene homolog 2 antibody
      • RRAS 2 antibody
      • RRAS2 antibody
      • RRAS2_HUMAN antibody
      • TC 21 antibody
      • TC21 antibody
      • Teratocarcinoma oncogene antibody
      • Teratocarcinoma oncogene TC21 antibody
      see all

    Images

    • Flow Cytometry - Anti-TC21 antibody [EM-50] (Phycoerythrin) (ab230662)
      Flow Cytometry - Anti-TC21 antibody [EM-50] (Phycoerythrin) (ab230662)

      Flow cytometric analysis of HEK-293 (human epithelial cell line from embryonic kidney) TC21 transfectants labeling TC21 with ab230662 (Red).

    References

    ab230662 has not yet been referenced specifically in any publications.

    Publishing research using ab230662? Please let us know so that we can cite the reference in this datasheet.

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