Anti-TCF12 antibody (ab91592)
Key features and details
- Rabbit polyclonal to TCF12
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TCF12 antibody
See all TCF12 primary antibodies -
Description
Rabbit polyclonal to TCF12 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Chimpanzee, Lizard, Rhesus monkey, Gorilla, Chinese hamster, Orangutan, Elephant -
Immunogen
Synthetic peptide within Human TCF12 aa 1-50 (N terminal). The exact sequence is proprietary.
Database link: NP_996919.1 -
Positive control
- Human Breast Carcinoma, Human Colon Carcinoma
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: Tris buffered saline, 0.1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab91592 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/100 - 1/500. Antigen retrieval is not essential but may optimise staining.
Antigen retrieval with Tris-EDTA pH9.0 buffer will enhance staining. |
Notes |
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IHC-P
1/100 - 1/500. Antigen retrieval is not essential but may optimise staining. Antigen retrieval with Tris-EDTA pH9.0 buffer will enhance staining. |
Target
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Function
Binds specifically to oligomers of E-box motifs. May play important roles during development of the nervous system as well as in other organ systems. -
Tissue specificity
Expressed in several tissues and cell types including skeletal muscle, thymus, and a B-cell line. -
Sequence similarities
Contains 1 basic helix-loop-helix (bHLH) domain. -
Domain
the 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. -
Post-translational
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 509039 Cow
- Entrez Gene: 6938 Human
- Entrez Gene: 21406 Mouse
- Entrez Gene: 25720 Rat
- Omim: 600480 Human
- SwissProt: Q99081 Human
- SwissProt: Q61286 Mouse
- SwissProt: P51514 Rat
see all -
Alternative names
- bHLHb20 antibody
- Class B basic helix-loop-helix protein 20 antibody
- DNA binding protein HTF4 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab91592 has not yet been referenced specifically in any publications.