Anti-TCF19/SC1 antibody (ab230005)
Key features and details
- Rabbit polyclonal to TCF19/SC1
- Suitable for: WB, IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-TCF19/SC1 antibody
See all TCF19/SC1 primary antibodies -
Description
Rabbit polyclonal to TCF19/SC1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Rat, Human
Predicted to work with: Chimpanzee, Rhesus monkey -
Immunogen
Recombinant fragment corresponding to Human TCF19/SC1 aa 1-300.
Database link: Q9Y242 -
Positive control
- WB: HEK-293T whole cell lysate; Rat thymus tissue lysate. IHC-P: Human testis tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab230005 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (1) |
1/1000 - 1/5000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).
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IHC-P |
1/20 - 1/200.
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Notes |
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WB
1/1000 - 1/5000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa). |
IHC-P
1/20 - 1/200. |
Target
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Function
Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression. -
Sequence similarities
Contains 1 FHA domain.
Contains 1 PHD-type zinc finger. -
Developmental stage
Growth regulated. -
Post-translational
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 100190896 Chimpanzee
- Entrez Gene: 6941 Human
- Entrez Gene: 406195 Rat
- Entrez Gene: 714141 Rhesus monkey
- Omim: 600912 Human
- SwissProt: Q7YR48 Chimpanzee
- SwissProt: Q9Y242 Human
- SwissProt: Q5TM48 Rhesus monkey
see all -
Alternative names
- SC 1 antibody
- SC1 antibody
- TCF 19 antibody
see all
Images
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All lanes : Anti-TCF19/SC1 antibody (ab230005) at 1/1000 dilution
Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
Lane 2 : Rat thymus lysate
Secondary
All lanes : Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa -
Paraffin-embedded human testis tissue stained for TCF19/SC1 using ab230005 at 1/100 dilution in immunohistochemical analysis.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab230005 has been referenced in 1 publication.
- Xu G et al. LncRNA MIR194-2HG Promotes Cell Proliferation and Metastasis via Regulation of miR-1207-5p/TCF19/Wnt/ß-Catenin Signaling in Liver Cancer. Onco Targets Ther 13:9887-9899 (2020). PubMed: 33116574