For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome

We use cookies to make our site as useful as possible.

Our Cookie Policy explains how you can opt-out of the cookies we use.

If you continue without changing your cookie settings, we'll assume you’re happy with this.

Continue Continue

United States
Your country/region is currently set to:

If incorrect, please enter your country/region into the box below, to view site information related to your country/region.

Call (888) 77-ABCAM (22226) or contact us
Need help? Contact us

  • My account
  • Sign out
Sign in or Register with us

Welcome

Sign in or

Don't have an account?

Register with us
My basket
Quick order
Abcam homepage

  • Research Products
    By product type
    Primary antibodies
    Secondary antibodies
    ELISA and Matched Antibody Pair Kits
    Cell and tissue imaging tools
    Cellular and biochemical assays
    By product type
    Proteins and Peptides
    Proteomics tools
    Agonists, activators, antagonists and inhibitors
    Lysates
    Multiplex Assays
    By research area
    Cancer
    Cardiovascular
    Cell Biology
    Epigenetics
    Metabolism
    Developmental Biology
    By research area
    Immunology
    Microbiology
    Neuroscience
    Signal Transduction
    Stem Cells
  • Diagnostic & Therapeutic Solutions
    Custom solutions & partnerships

    Custom antibody development and commercial partnerships to advance your diagnostic and therapeutic discovery.

    Create custom solutions with us

    Partner with us

  • Support
    • Protocols & troubleshooting
    • Technical FAQs
    • Get technical help
    • RabMAb Advantages
    • Buying FAQs
    • Antibody Guide
    • Scientific webinars
    • Biochemical product FAQ
    • Support resources
    • eProcurement
    Check out our protocols

    Visit protocols and troubleshooting or check them out using the Abcam app for iPhone

    Protocols and troubleshooting

    iPhone app

  • Events
    • Conference calendar
    • Cancer
    • Cardiovascular
    • Epigenetics & Nuclear signaling
    • Immunology
    • Neuroscience
    • Stem cells
    • Tradeshows
    • Scientific webinars
    Keep up to date with the latest events

    Full event breakdown with abstracts, speakers, registration and more

    View global event calendar

  • Pathways
    Cell signalling pathways

    View all pathways

    View all interactive pathways

  1. Link

    tcp1-alphaccta-antibody-91a-ab240903.pdf

  1. Send me a copy of this email
    I agree to the terms and conditions.
Signal Transduction Cytoskeleton / ECM Cytoskeleton Microfilaments Actin etc Actin
Share by email

Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)

  • Datasheet
Submit a review Submit a question

Product price, shipping and contact information

Currently unavailable

Sorry, we can't display this right now.

Please contact us to place your order, or try again later.

 

Loading size & price…

 

Shipping and order information

Abpromise

Guaranteed product quality, expert customer support.

Find out more.

  • Western blot - Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)
  • Immunocytochemistry/ Immunofluorescence - Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)
  • Immunocytochemistry/ Immunofluorescence - Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)

Add compatible products

Primary

Product image

 

Protein

Product image

 

Unfortunately, one or more of the products below are unavailable in your country/region.

Sorry, we can't display this right now.
Please contact us to place your order, or try again later.

View more associated products

  • Datasheet
  • References
  • Protocols

Overview

  • Product name

    Anti-TCP1 alpha/CCTA antibody [91a]
    See all TCP1 alpha/CCTA primary antibodies
  • Description

    Rat monoclonal [91a] to TCP1 alpha/CCTA
  • Host species

    Rat
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Mouse TCP1 alpha/CCTA (C terminal).
    Database link: P11983

  • Positive control

    • WB: A431 and HEK-293 cell lysates. ICC/IF: HeLa cells.
  • General notes

     This product was previously labelled as TCP1 alpha

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.09% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purified from TCS.
  • Clonality

    Monoclonal
  • Clone number

    91a
  • Isotype

    IgG
  • Research areas

    • Signal Transduction
    • Cytoskeleton / ECM
    • Cytoskeleton
    • Microfilaments
    • Actin etc
    • Actin
    • Signal Transduction
    • Protein Trafficking
    • Chaperones
    • Other Chaperones

Associated products

  • Compatible Secondaries

    • Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
    • Goat Anti-Rat IgG H&L (HRP) (ab205720)
  • Isotype control

    • Rat IgG - Isotype Control (ab37361)
  • Positive Controls

    • A431 whole cell lysate (ab30132)
    • HEK293 whole cell lysate (ab7902)
    • A431 whole cell lysate (ab7909)
  • Recombinant Protein

    • Recombinant Human TCP1 alpha/CCTA protein (ab101043)
  • Related Products

    • Recombinant Human TCP1 alpha/CCTA protein (ab101043)

Applications

Our Abpromise guarantee covers the use of ab240903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 60 kDa.
ICC/IF 1/100.

Target

  • Function

    Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.
  • Sequence similarities

    Belongs to the TCP-1 chaperonin family.
  • Cellular localization

    Cytoplasm. Cytoplasm > cytoskeleton > centrosome.
  • Target information above from: UniProt accession P17987 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 6950 Human
    • Omim: 186980 Human
    • SwissProt: P17987 Human
    • Unigene: 363137 Human
    • Alternative names

      • AI528772 antibody
      • c-cpn antibody
      • CCT alpha antibody
      • CCT antibody
      • CCT-alpha antibody
      • CCT1 antibody
      • Ccta antibody
      • CCTalpha antibody
      • D6S230E antibody
      • MGC133746 antibody
      • p63 antibody
      • T complex 1 antibody
      • T complex protein 1 alpha subunit antibody
      • T complex protein 1 antibody
      • T-complex homolog TCP1 antibody
      • T-complex protein 1 subunit alpha antibody
      • T-complex protein 1 subunit alpha B antibody
      • Tailless complex polypeptide 1 antibody
      • Tailless complex polypeptide 1A antibody
      • Tailless complex polypeptide 1B antibody
      • TCP 1 alpha antibody
      • Tcp-1 antibody
      • TCP-1-alpha antibody
      • TCP1 antibody
      • TCPA_HUMAN antibody
      • Tp63 antibody
      • TRic antibody
      see all

    Images

    • Western blot - Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)
      Western blot - Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)
      All lanes : Anti-TCP1 alpha/CCTA antibody [91a] (ab240903) at 1/1000 dilution

      Lane 1 : A431 (human epidermoid carcinoma cell line) cell lysate
      Lane 2 : HEK-293 (human epithelial cell line from embryonic kidney) cell lysate

      Predicted band size: 60 kDa

    • Immunocytochemistry/ Immunofluorescence - Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)
      Immunocytochemistry/ Immunofluorescence - Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)

      Immunofluorescent analysis of 4% paraformaldehyde-fixed HeLa (heat shocked for 1 hour at 42°)(human epithelial cell line from cervix adenocarcinoma) cells labeling TCP1 alpha/CCTA with ab240903 at 1/100 dilution for 12 hours at 4°C, followed by R-PE Goat Anti-Rat (yellow) at 1/200 dilution for 2 hours at room temperature (yellow). The nuclear counter stain is DAPI (blue). 

      A: DAPI, B: TCP1 alpha/CCTA, C: Composite.

    • Immunocytochemistry/ Immunofluorescence - Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)
      Immunocytochemistry/ Immunofluorescence - Anti-TCP1 alpha/CCTA antibody [91a] (ab240903)

      Immunofluorescent analysis of 2% paraformaldehyde-fixed HeLa (heat shocked for 1 hour at 42°) (human epithelial cell line from cervix adenocarcinoma) cells labeling TCP1 alpha/CCTA with ab240903 at 1/100 dilution for 12 hours at 4°C, followed by APC Goat Anti-Rat at 1/200 dilution for 2 hours at room temperature (red). The nuclear counter stain is DAPI (blue). 

      A: DAPI, B: TCP1 alpha/CCTA, C: Composite.

    Datasheets and documents

    • Datasheet
  • References

    ab240903 has not yet been referenced specifically in any publications.

    Publishing research using ab240903? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab240903.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Get resources and offers direct to your inbox Sign up
    A-Z by research area
    • Cancer
    • Cardiovascular
    • Cell biology
    • Developmental biology
    • Epigenetics & Nuclear signaling
    • Immunology
    • Metabolism
    • Microbiology
    • Neuroscience
    • Signal transduction
    • Stem cells
    A-Z by product type
    • Primary antibodies
    • Secondary antibodies
    • Biochemicals
    • Isotype controls
    • Flow cytometry multi-color selector
    • Kits
    • Loading controls
    • Lysates
    • Peptides
    • Proteins
    • Slides
    • Tags and cell markers
    • Tools & Reagents
    Help & support
    • Support
    • Make an Inquiry
    • Protocols & advice
    • Buying FAQs
    • RabMAb products
    • Biochemical product FAQs
    Company
    • Investor relations
    • Company news
    • Careers
    • About us
    • Blog
    Events
    • Tradeshows
    • Conferences
    International websites
    • abcam.cn
    • abcam.co.jp

    Join with us

    • LinkedIn
    • facebook
    • Twitter
    • YouTube
    • Terms of sale
    • Website terms of use
    • Cookie policy
    • Privacy policy
    • Legal
    • Modern slavery statement
    © 1998-2019 Abcam plc. All rights reserved.