Overview

  • Product name

    Anti-TCR alpha + TCR beta antibody [KJ12-98]
    See all TCR alpha + TCR beta primary antibodies
  • Description

    Mouse monoclonal [KJ12-98] to TCR alpha + TCR beta
  • Host species

    Mouse
  • Specificity

    The 3DT-52.5 TcR idiotype in Mouse
  • Tested applications

    Suitable for: IP, ELISA, Inhibition Assay, Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    3DT-52.5 (a mouse T cell hybridoma)

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Clonality

    Monoclonal
  • Clone number

    KJ12-98
  • Myeloma

    P3x63-Ag8.653
  • Isotype

    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab71525 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP
ELISA
Inhibition Assay
Flow Cyt
  • Application notes
    ELISA: Use at an assay dependent dilution.
    Flow Cyt: 1/5 - 1/10.
    IP: Use at an assay dependent dilution.
    Inhib: Use at an assay dependent dilution.
    If the antibody is coupled to beads it can also be used to stimulate the target T cell hybridoma.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance

      The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
    • Cellular localization

      Type I membrane protein.
    • Database links

    • Alternative names

      • FLJ22602 antibody
      • MGC117436 antibody
      • MGC22624 antibody
      • MGC23964 antibody
      • MGC71411 antibody
      • T cell antigen receptor alpha polypeptide antibody
      • T cell antigen receptor beta polypeptide T cell receptor beta cluster antibody
      • T cell receptor alpha (V D J C) antibody
      • T cell receptor alpha chain C region antibody
      • T cell receptor alpha constant antibody
      • T cell receptor alpha locus antibody
      • T cell receptor beta cluster antibody
      • T cell receptor beta locus antibody
      • TCRA antibody
      • TCRB antibody
      • TCRD antibody
      • TRA antibody
      • TRAC antibody
      • TRB antibody
      see all

    References

    ab71525 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab71525.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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