Key features and details
- Mouse monoclonal [R73] to TCR alpha + TCR beta (FITC)
- Suitable for: Flow Cyt
- Reacts with: Rat
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Product nameAnti-TCR alpha + TCR beta antibody [R73] (FITC)
See all TCR alpha + TCR beta primary antibodies
DescriptionMouse monoclonal [R73] to TCR alpha + TCR beta (FITC)
ConjugationFITC. Ex: 493nm, Em: 528nm
Specificityab176542 recognizes TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Rat
Predicted to work with: Non human primates
Tissue, cells or virus corresponding to Rat TCR alpha + TCR beta. Rat T blasts and erythrocytes.
Database link: 24820
Storage instructionsShipped at 4°C. Store at +4°C. Store In the Dark.
Storage bufferpH: 7.40
Preservative: 0.098% Sodium azide
Constituent: 99% PBS
Concentration information loading...
Purification notesThis conjugate is made from a highly purified antibody (>95% by SDS-PAGE); free of unconjugated FITC.
Our Abpromise guarantee covers the use of ab176542 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
RelevanceThe receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
Cellular localizationType I membrane protein.
- FLJ22602 antibody
- MGC117436 antibody
- MGC22624 antibody
ab176542 has not yet been referenced specifically in any publications.