Key features and details
- Rabbit polyclonal to TCTN1
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-TCTN1 antibody
DescriptionRabbit polyclonal to TCTN1
Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
15 amino acid synthetic peptide near the N-terminus of Human TCTN1 (NP_001076007).
- Mouse kidney tissue lysate, Human kidney tissue
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab105381 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 64 kDa.|
|IHC-P||Use a concentration of 5 µg/ml.|
FunctionRegulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23.
Sequence similaritiesBelongs to the tectonic family.
- Information by UniProt
- JBTS13 antibody
- TCTN1 antibody
- TECT1 antibody
ab105381 at 5 µg/ml staining TCTN1 in Human kidney tissue by Immunohistochemistry
Lane 1 : Anti-TCTN1 antibody (ab105381) at 1 µg/ml
Lane 2 : Anti-TCTN1 antibody (ab105381) at 2 µg/ml
All lanes : Mouse kidney tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 64 kDa
Immunofluorescence of TCTN1 in Human Kidney cells using ab105381 at 20 ug/ml.
ab105381 has been referenced in 2 publications.
- Liu W et al. MiR-1256 suppresses proliferation and migration of non-small cell lung cancer via regulating TCTN1. Oncol Lett 16:1708-1714 (2018). PubMed: 30008857
- Meng D et al. Expression and prognostic significance of TCTN1 in human glioblastoma. J Transl Med 12:288 (2014). IHC ; Human . PubMed: 25304031