Overview

  • Product name

  • Description

    Rabbit polyclonal to TEAD3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from an internal region of Human TEAD3.

  • Positive control

    • HUVEC cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab138246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 49 kDa.

Target

  • Function

    Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
  • Tissue specificity

    Preferentially expressed in the placenta.
  • Sequence similarities

    Contains 1 TEA DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • DTEF 1 antibody
    • DTEF-1 antibody
    • DTEF1 antibody
    • ETFR 1 antibody
    • ETFR1 antibody
    • TEA domain family member 3 antibody
    • TEA domain family member 5 antibody
    • TEAD 3 antibody
    • TEAD-3 antibody
    • Tead3 antibody
    • TEAD3_HUMAN antibody
    • TEAD5 antibody
    • TEF 5 antibody
    • TEF5 antibody
    • Transcriptional enhancer factor 5 antibody
    • Transcriptional enhancer factor TEF 5 (DTEF 1) antibody
    • Transcriptional enhancer factor TEF 5 antibody
    • Transcriptional enhancer factor TEF-5 antibody
    see all

Images

  • Anti-TEAD3 antibody (ab138246) at 1/500 dilution + HUVEC cell lysate at 30 µg

    Predicted band size: 49 kDa

References

ab138246 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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