• Product name

  • Description

    Rabbit polyclonal to Telethonin
  • Host species

  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein corresponding to Human Telethonin.
    Database link: O15273

  • Positive control

    • Mouse heart and skeletal muscle lysates; Rat heart and skeletal muscle lysates; HeLa cells.


  • Form

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab210773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 19 kDa.
IHC-P 1/50 - 1/200.
ICC/IF 1/10 - 1/100.


  • Function

    Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk.
  • Tissue specificity

    Heart and skeletal muscle.
  • Involvement in disease

    Defects in TCAP are a cause of cardiomyopathy familial hypertrophic (CMH) [MIM:192600]; also designated FHC or HCM. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
    Defects in TCAP are a cause of limb-girdle muscular dystrophy type 2G (LGMD2G) [MIM:601954]. LGMD2G is an autosomal recessive degenerative myopathy characterized by proximal and distal muscle weakness and atrophy in the limbs, dystrophic changes on muscle biopsy, and absence of telethonin. Cardiac muscle is involved in a subset of patients.
    Defects in TCAP are the cause of cardiomyopathy dilated type 1N (CMD1N) [MIM:607487]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
  • Cellular localization

    Cytoplasm > myofibril > sarcomere.
  • Information by UniProt
  • Database links

  • Alternative names

    • 19 kDa sarcomeric protein antibody
    • CMD1N antibody
    • CMH25 antibody
    • LGMD2G antibody
    • Limb girdle muscular dystrophy 2G (autosomal recessive) antibody
    • T-cap antibody
    • Tcap antibody
    • TELE antibody
    • Telethonin antibody
    • TELT_HUMAN antibody
    • Titin cap protein antibody
    • Titin-cap antibody
    see all


  • All lanes : Anti-Telethonin antibody (ab210773) at 1/500 dilution

    Lane 1 : Mouse heart extract
    Lane 2 : Mouse skeletal muscle extract
    Lane 3 : Rat heart extract
    Lanes 4-5 : Rat skeletal muscle extract

    Predicted band size: 19 kDa

  • Immunofluorescent analysis of HeLa cells labeling Telethonin with ab210773 at 1/10 dilution (red). Blue: DAPI for nuclear staining.


ab210773 has not yet been referenced specifically in any publications.

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