Temozolomide, DNA alkylating/methylating chemotherapeutic agent (ab141055)

Overview

  • Product name
    Temozolomide, DNA alkylating/methylating chemotherapeutic agent
  • Description
    DNA alkylating/methylating chemotherapeutic agent
  • Biological description
    DNA alkylating/methylating chemotherapeutic agent. Inhibits DNA replication. Anti-cancer and apoptotic activity in vitro and in vivo. Crosses the blood-brain barrier.
  • Purity
    > 99%
  • CAS Number
    85622-93-1
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Prasad G  et al. Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide. Neuro Oncol 13:384-92 (2011). Read more (PubMed: 21317208) »
  • Addeo R & Caraglia M Combining temozolomide with other antitumor drugs and target-based agents in the treatment of brain metastases: an unending quest or chasing a chimera? Expert Opin Investig Drugs 20:881-95 (2011). Read more (PubMed: 21529310) »
  • Fukushima T  et al. Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT. Anticancer Res 29:4845-54 (2009). Read more (PubMed: 20032445) »

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