Overview

  • Product name

  • Description

    Rabbit polyclonal to Tenascin C
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment (His-tag) corresponding to Rat Tenascin C aa 513-621. (Expressed in E.coli).
    Sequence:

    DGQCICEDGFTGSDCAELSCPGDCHGHGRCVNGQCICHEGFTGXDCKEQR CPSDCHGQGRCEDGQCICHEGFTGLDCGQRSCPNDCSNQGQCVAGRCICN EGYTGVDCS


    Database link: B2LYI9

  • Positive control

    • IHC-P: Rat kidney tissue. WB: Rat placenta lysate; Recombinant rat Tenascin C protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab231179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 222 kDa.
IHC-P Use a concentration of 5 - 20 µg/ml.

Target

  • Function

    Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
  • Sequence similarities

    Belongs to the tenascin family.
    Contains 15 EGF-like domains.
    Contains 1 fibrinogen C-terminal domain.
    Contains 15 fibronectin type-III domains.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links

  • Alternative names

    • 150 225 antibody
    • Cytotactin antibody
    • Glioma associated extracellular matrix antigen antibody
    • Glioma-associated-extracellular matrix antigen antibody
    • GMEM antibody
    • GP 150 225 antibody
    • GP 150-225 antibody
    • GP antibody
    • Hexabrachion antibody
    • HXB antibody
    • JI antibody
    • MGC167029 antibody
    • Miotendinous antigen antibody
    • Myotendinous antigen antibody
    • Neuronectin antibody
    • TENA_HUMAN antibody
    • Tenascin antibody
    • Tenascin-C antibody
    • Tenascin-C isoform 14/AD1/16 antibody
    • TenascinC antibody
    • TN antibody
    • TN C antibody
    • TN-C antibody
    • TNC antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded rat kidney tissue stained for Tenascin C using ab231179 at 20 µg/ml in immunohistochemical analysis. DAB staining.

  • Anti-Tenascin C antibody (ab231179) at 2 µg/ml + Recombinant rat Tenascin C protein

    Predicted band size: 222 kDa

  • Anti-Tenascin C antibody (ab231179) at 2 µg/ml + Rat placenta lysate

    Predicted band size: 222 kDa

  • All lanes : Anti-Tenascin C antibody (ab231179) at 1.5 µg/ml

    Lane 1 : Rat stomach lysate
    Lane 2 : Rat placenta lysate

    Secondary
    All lanes : HRP-Linked Guinea pig Anti-Rabbit antibody at 1/1000 dilution

    Predicted band size: 222 kDa

References

ab231179 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab231179.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up