• Product name
    Anti-Tenascin C antibody [DB7]
    See all Tenascin C primary antibodies
  • Description
    Mouse monoclonal [DB7] to Tenascin C
  • Host species
  • Specificity
    ab86182 reacts with the fibrinogen like knob domain of Tenascin C.
  • Tested applications
    Suitable for: IP, WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tenascin polypeptides from spent culture supernatant of human fibroblasts isolated by affinity chromatography.

  • General notes

    ab86182 is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.



Our Abpromise guarantee covers the use of ab86182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
WB 1/1000. Predicted molecular weight: 241 kDa.
IHC-P Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.


  • Function
    Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
  • Sequence similarities
    Belongs to the tenascin family.
    Contains 15 EGF-like domains.
    Contains 1 fibrinogen C-terminal domain.
    Contains 15 fibronectin type-III domains.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • 150 225 antibody
    • Cytotactin antibody
    • Glioma associated extracellular matrix antigen antibody
    • Glioma-associated-extracellular matrix antigen antibody
    • GMEM antibody
    • GP 150 225 antibody
    • GP 150-225 antibody
    • GP antibody
    • Hexabrachion antibody
    • HXB antibody
    • JI antibody
    • MGC167029 antibody
    • Miotendinous antigen antibody
    • Myotendinous antigen antibody
    • Neuronectin antibody
    • TENA_HUMAN antibody
    • Tenascin antibody
    • Tenascin-C antibody
    • Tenascin-C isoform 14/AD1/16 antibody
    • TenascinC antibody
    • TN antibody
    • TN C antibody
    • TN-C antibody
    • TNC antibody
    see all


  • Immunohistochemical analysis of Human cornea tissue, staining Tenascin C wih ab86182.

    Tissue was taken from healthy patients (left) or patients with granular dystrophy (right). Sections were blocked with blocking solution for 30 minutes at room temperature before incubation with primary antibody (1/50) overnight at 4°C. Staining was detected with DAB.


This product has been referenced in:
  • Gökçinar-Yagci B  et al. Generation of human umbilical cord vein CD146+ perivascular cell origined three-dimensional vascular construct. Microvasc Res 118:101-112 (2018). IHC-P . Read more (PubMed: 29550275) »
  • Li Y  et al. Differentiation of Human Amniotic Mesenchymal Stem Cells into Human Anterior Cruciate Ligament Fibroblast Cells by In Vitro Coculture. Biomed Res Int 2017:7360354 (2017). Read more (PubMed: 29085840) »

See all 4 Publications for this product

Customer reviews and Q&As

Muchas gracias por tu respuesta.

Es importante que todos los anticuerpos que escojas para llevar a cabo IHC-P en tejido humano estén validados (y por tanto garantizados por Abcam) para funcionar en esta especie y aplicación. Est...

Read More

Thank you once again for your recent enquiries and I appreciate your patience in waiting for a reply.

I have now received information from the originator, who have confirm that regrettably, we do not have a blocking peptide to provide for th...

Read More


Sign up