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    tenc1tensin-2-antibody-ab96381.pdf

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Signal Transduction Protein Phosphorylation Ser / Thr Kinases PKB / AKT
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Anti-TENC1/Tensin-2 antibody (ab96381)

  • Datasheet
  • SDS
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Western blot - Anti-TENC1/Tensin-2 antibody (ab96381)

    Key features and details

    • Rabbit polyclonal to TENC1/Tensin-2
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    You may also be interested in

    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-TENC1/Tensin-2 antibody
      See all TENC1/Tensin-2 primary antibodies
    • Description

      Rabbit polyclonal to TENC1/Tensin-2
    • Host species

      Rabbit
    • Tested applications

      Suitable for: WBmore details
    • Species reactivity

      Reacts with: Human
      Predicted to work with: Mouse
    • Immunogen

      Recombinant fragment corresponding to Human TENC1/Tensin-2 aa 1098-1419.

    • Positive control

      • HeLa whole cell lysate
    • General notes

       This product was previously labelled as TENC1

       

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
    • Storage buffer

      pH: 7.00
      Preservative: 0.01% Thimerosal (merthiolate)
      Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Signal Transduction
      • Protein Phosphorylation
      • Ser / Thr Kinases
      • PKB / AKT

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
    • Positive Controls

      • HeLa whole cell lysate (ab29545)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab96381 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB
    1/500 - 1/3000. Predicted molecular weight: 154 kDa.
    Notes
    WB
    1/500 - 1/3000. Predicted molecular weight: 154 kDa.

    Target

    • Function

      Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling.
    • Tissue specificity

      Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine.
    • Sequence similarities

      Contains 1 C2 tensin-type domain.
      Contains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 phosphatase tensin-type domain.
      Contains 1 SH2 domain.
    • Cellular localization

      Cell junction > focal adhesion. Cell membrane. Detected at the end of actin stress fibers.
    • Target information above from: UniProt accession Q63HR2 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 23371 Human
      • Entrez Gene: 209039 Mouse
      • Omim: 607717 Human
      • SwissProt: Q63HR2 Human
      • SwissProt: Q8CGB6 Mouse
      • Unigene: 343334 Human
      • Unigene: 6147 Human
      • Unigene: 29389 Mouse
      • Alternative names

        • C1 domain containing phosphatase and tensin homolog antibody
        • C1 domain-containing phosphatase and tensin homolog antibody
        • C1 TEN antibody
        • C1-TEN antibody
        • C1TEN antibody
        • DKFZp686D13244 antibody
        • FLJ16320 antibody
        • KIAA1075 antibody
        • TENC 1 antibody
        • TENC1 antibody
        • TENC1_HUMAN antibody
        • Tensin 2 antibody
        • Tensin like C1 domain containing phosphatase antibody
        • Tensin-2 antibody
        • Tensin-like C1 domain-containing phosphatase antibody
        • TNS2 antibody
        see all

      Images

      • Western blot - Anti-TENC1/Tensin-2 antibody (ab96381)
        Western blot - Anti-TENC1/Tensin-2 antibody (ab96381)
        Anti-TENC1/Tensin-2 antibody (ab96381) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

        Predicted band size: 154 kDa



        5% SDS-PAGE

      Protocols

      • Western blot protocols

      Click here to view the general protocols

      Datasheets and documents

      • SDS download

      • Datasheet download

        Download

      References (2)

      Publishing research using ab96381? Please let us know so that we can cite the reference in this datasheet.

      ab96381 has been referenced in 2 publications.

      • Ben Khalaf N  et al. The mouse intron-nested gene, Israa, is expressed in the lymphoid organs and involved in T-cell activation and signaling. Mol Immunol 111:209-219 (2019). PubMed: 31096062
      • Karere GM  et al. Identification of candidate genes encoding an LDL-C QTL in baboons. J Lipid Res 54:1776-85 (2013). PubMed: 23596326

      Customer reviews and Q&As

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      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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