Anti-TENC1/Tensin-2 antibody (ab96381)
Key features and details
- Rabbit polyclonal to TENC1/Tensin-2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-TENC1/Tensin-2 antibody
See all TENC1/Tensin-2 primary antibodies -
Description
Rabbit polyclonal to TENC1/Tensin-2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse
-
Immunogen
Recombinant fragment corresponding to Human TENC1/Tensin-2 aa 1098-1419.
-
Positive control
- HeLa whole cell lysate
-
General notes
This product was previously labelled as TENC1
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96381 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 154 kDa.
|
| Notes |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 154 kDa. |
Target
-
Function
Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling. -
Tissue specificity
Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine. -
Sequence similarities
Contains 1 C2 tensin-type domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 phosphatase tensin-type domain.
Contains 1 SH2 domain. -
Cellular localization
Cell junction > focal adhesion. Cell membrane. Detected at the end of actin stress fibers. - Information by UniProt
-
Database links
- Entrez Gene: 23371 Human
- Entrez Gene: 209039 Mouse
- Omim: 607717 Human
- SwissProt: Q63HR2 Human
- SwissProt: Q8CGB6 Mouse
- Unigene: 343334 Human
- Unigene: 6147 Human
- Unigene: 29389 Mouse
-
Alternative names
- C1 domain containing phosphatase and tensin homolog antibody
- C1 domain-containing phosphatase and tensin homolog antibody
- C1 TEN antibody
see all
Images
-
Western blot - Anti-TENC1/Tensin-2 antibody (ab96381)Anti-TENC1/Tensin-2 antibody (ab96381) at 1/1000 dilution + HeLa whole cell lysate at 30 µg
Predicted band size: 154 kDa
5% SDS-PAGE
Datasheets and documents
-
SDS download
-
Datasheet download
References (2)
ab96381 has been referenced in 2 publications.
- Ben Khalaf N et al. The mouse intron-nested gene, Israa, is expressed in the lymphoid organs and involved in T-cell activation and signaling. Mol Immunol 111:209-219 (2019). PubMed: 31096062
- Karere GM et al. Identification of candidate genes encoding an LDL-C QTL in baboons. J Lipid Res 54:1776-85 (2013). PubMed: 23596326