Overview

  • Product name

    Anti-Teneurin-4 antibody
  • Description

    Sheep polyclonal to Teneurin-4
  • Host species

    Sheep
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment corresponding to Human Teneurin-4 aa 61-340. E. coli-derived
    Sequence:

    KDIVPQEAEE FCRTGANFTL RELGLEEVTP PHGTLYRTDI GLPHCGYSMG AGSDADMEAD TVLSPEHPVR LWGRSTRSGR SSCLSSRANS NLTLTDTEHE NTETDHPGGL QNHARLRTPP PPLSHAHTPN QHHAASINSL NRGNFTPRSN PSPAPTDHSL SGEPPAGGAQ EPAHAQENWL LNSNIPLETR NLGKQPFLGT LQDNLIEMDI LGASRHDGAY SDGHFLFKPG GTSPLFCTTS PGYPLTSSTV YSPPPRPLPR STFARPAFNL KKPSKYCNWK


    Database link: Q6N022

  • Positive control

    • Lysate of mouse embryonic tissue

Properties

  • Form

    Lyophilised:Reconstitute the antibody with 100 uL sterile PBS and the final concentration is 500 ug/mL. Reconstituted antibody can also be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    The IgG fraction of immunized serum was purified by antigen affinity chromatography and lyophilized from a 0.2 µm filtered solution in phosphate-buffered saline (PBS)
  • Clonality

    Polyclonal
  • Isotype

    IgG

Associated products

Applications

Our Abpromise guarantee covers the use of ab215052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000.

Target

  • Function

    Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of small-diameter axons in the central nervous system (CNS). Promotes activation of focal adhesion kinase. May function as a cellular signal transducer.
  • Sequence similarities

    Belongs to the tenascin family. Teneurin subfamily.
    Contains 8 EGF-like domains.
    Contains 5 NHL repeats.
    Contains 1 teneurin N-terminal domain.
    Contains 23 YD repeats.
  • Domain

    EGF-like domains 2 and 5 which have an odd number of cysteines might enable the formation of intermolecular disulfide bonds.
    Cytoplasmic proline-rich regions could serve as docking domains for intracellular SH3-containing proteins.
  • Cellular localization

    Membrane. Nucleus. Cytoplasm. Cell projection.
  • Information by UniProt
  • Database links

  • Alternative names

    • Protein Odd Oz/ten-m homolog 4 antibody
    • Ten-4 antibody
    • Ten-m4 antibody
    • TEN4_HUMAN antibody
    • Tenascin-M4 antibody
    • Teneurin transmembrane protein 4 antibody
    • Teneurin-4 antibody
    • tenm4 antibody
    see all

Images

  • Anti-Teneurin-4 antibody (ab215052) at 1/1000 dilution + lysate from mouse embryonic tissue

References

ab215052 has not yet been referenced specifically in any publications.

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