Overview

  • Product name

    Tenovin-1, p53 Activator
  • Description

    p53 Activator
  • Biological description

    p53 Activator. Protects p53 from MDM2 mediated degradation through SirT1 inhibition. Inhibits downstream histone acetylation, activates p21CIP/WAF1. Potent antiproliferative effects in vitro.
  • Purity

    > 98%
  • CAS Number

    380315-80-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Lain S  et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell 13:454-63 (2008). Read more (PubMed: 18455128) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120889.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up