Anti-Tensin 1 antibody (ab167660)

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Overview

  • Product name

    Anti-Tensin 1 antibody
    See all Tensin 1 primary antibodies

  • Description

    Mouse polyclonal to Tensin 1

  • Host species

    Mouse

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant fragment corresponding to Human Tensin 1 aa 1-352.
    Sequence:

    MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSK HGGNYLLFNLSERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTW LNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFY EDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESK GGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGDILLKC YHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGM EDGNKQNTNSQSIGSISGGLEDQYTWPDTHWPSQS


    Database link: Q9HBL0

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • Tensin 1 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab167660 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa.

Target

  • Function

    Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.

  • Tissue specificity

    Ubiquitous.

  • Sequence similarities

    Contains 1 C2 tensin-type domain.
    Contains 1 phosphatase tensin-type domain.
    Contains 1 SH2 domain.

  • Post-translational
    modifications

    Rapidly cleaved by calpain II.

  • Cellular localization

    Cell surface. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.
  • Information by UniProt

  • Database links

    • Alternative names

      • matrix-remodelling associated 6 antibody
      • Matrix-remodelling-associated protein 6 antibody
      • MGC88584 antibody
      • MST091 antibody
      • MST122 antibody
      • MST127 antibody
      • MSTP091 antibody
      • MSTP122 antibody
      • MSTP127 antibody
      • MXRA6 antibody
      • TENS1_HUMAN antibody
      • Tensin antibody
      • Tensin-1 antibody
      • TNS antibody
      • TNS1 antibody
      see all

    Images

    • Western blot - Anti-Tensin 1 antibody (ab167660)
      Western blot - Anti-Tensin 1 antibody (ab167660)
      All lanes : Anti-Tensin 1 antibody (ab167660) at 1 µg/ml

      Lane 1 : Tensin 1 transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 15 µl per lane.

      Secondary
      All lanes : Goat Anti-Mouse IgG HRP


      Predicted band size: 44 kDa

    References

    This product has been referenced in:

    • Zhou H  et al. Elevated transgelin/TNS1 expression is a potential biomarker in human colorectal cancer. Oncotarget 9:1107-1113 (2018). Read more (PubMed: 29416680) »
    See 1 Publication for this product

    Publishing research using ab167660? Please let us know so that we can cite the reference in this datasheet.

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