Anti-Tensin 1 antibody (ab167660)

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Western blot - Anti-Tensin 1 antibody (ab167660)

    Key features and details

    • Mouse polyclonal to Tensin 1
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-Tensin 1 antibody
      See all Tensin 1 primary antibodies

    • Description

      Mouse polyclonal to Tensin 1

    • Host species

      Mouse

    • Tested applications

      Suitable for: WBmore details

    • Species reactivity

      Reacts with: Human

    • Immunogen

      Recombinant fragment corresponding to Human Tensin 1 aa 1-352.
      Sequence:

      MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSK HGGNYLLFNLSERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTW LNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFY EDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESK GGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGDILLKC YHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGM EDGNKQNTNSQSIGSISGGLEDQYTWPDTHWPSQS


      Database link: Q9HBL0
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • Positive control

      • Tensin 1 transfected 293T cell lysate

    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab167660 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa.

    Target

    • Function

      Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.

    • Tissue specificity

      Ubiquitous.

    • Sequence similarities

      Contains 1 C2 tensin-type domain.
      Contains 1 phosphatase tensin-type domain.
      Contains 1 SH2 domain.

    • Post-translational
      modifications

      Rapidly cleaved by calpain II.

    • Cellular localization

      Cell surface. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.
    • Information by UniProt

    • Database links

      • Alternative names

        • matrix-remodelling associated 6 antibody
        • Matrix-remodelling-associated protein 6 antibody
        • MGC88584 antibody
        • MST091 antibody
        • MST122 antibody
        • MST127 antibody
        • MSTP091 antibody
        • MSTP122 antibody
        • MSTP127 antibody
        • MXRA6 antibody
        • TENS1_HUMAN antibody
        • Tensin antibody
        • Tensin-1 antibody
        • TNS antibody
        • TNS1 antibody
        see all

      Images

      • Western blot - Anti-Tensin 1 antibody (ab167660)
        Western blot - Anti-Tensin 1 antibody (ab167660)
        All lanes : Anti-Tensin 1 antibody (ab167660) at 1 µg/ml

        Lane 1 : Tensin 1 transfected 293T cell lysate
        Lane 2 : Non-transfected 293T cell lysate

        Lysates/proteins at 15 µl per lane.

        Secondary
        All lanes : Goat Anti-Mouse IgG HRP


        Predicted band size: 44 kDa

      References (1)

      Publishing research using ab167660? Please let us know so that we can cite the reference in this datasheet.

      ab167660 has been referenced in 1 publication.

      • Zhou H  et al. Elevated transgelin/TNS1 expression is a potential biomarker in human colorectal cancer. Oncotarget 9:1107-1113 (2018). PubMed: 29416680

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