Overview

  • Product name

  • Description

    Goat polyclonal to Tensin 1
  • Host species

    Goat
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Synthetic peptide corresponding to Human Tensin 1 aa 902-914 (internal sequence) (Cysteine residue).
    Sequence:

    QYENQSPEATSPR


    Database link: Q9HBL0

  • Positive control

    • Human kidney tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab206117 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 2 - 4 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Contains 1 C2 tensin-type domain.
    Contains 1 phosphatase tensin-type domain.
    Contains 1 SH2 domain.
  • Post-translational
    modifications

    Rapidly cleaved by calpain II.
  • Cellular localization

    Cell surface. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.
  • Information by UniProt
  • Database links

  • Alternative names

    • matrix-remodelling associated 6 antibody
    • Matrix-remodelling-associated protein 6 antibody
    • MGC88584 antibody
    • MST091 antibody
    • MST122 antibody
    • MST127 antibody
    • MSTP091 antibody
    • MSTP122 antibody
    • MSTP127 antibody
    • MXRA6 antibody
    • TENS1_HUMAN antibody
    • Tensin antibody
    • Tensin-1 antibody
    • TNS antibody
    • TNS1 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Human kidney tissue labeling Tensin 1 with ab206117 at 2µg/ml.

References

ab206117 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab206117.
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