Tenuazonic Acid Copper Salt, Antineoplastic agent (ab144809)

Overview

  • Product name

    Tenuazonic Acid Copper Salt, Antineoplastic agent
  • Description

    Antineoplastic agent. Mycotoxin.
  • Biological description

    Antineoplastic agent. Mycotoxin. Inhibits protein synthesis. Inhibits TPA-induced ornithine decarboxylase activity. Photosystem II inhibitor. Shows antiviral, antibacterial and antitumor activity in vivo.
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (5S)-3-Acetyl-5-[(2S)-butan-2-yl]-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one copper salt
  • Molecular weight

    228.00
  • Molecular formula

    C10H14NO3.0.5Cu
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    [Cu+2].[O-]C1=C(C(=O)N[C@H]1[C@@H](C)CC)C(C)=O.CC(=O)C=1C(=O)N[C@@H]([C@@H](C)CC)C=1[O-]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Chen S  et al. In vivo assessment of effect of phytotoxin tenuazonic acid on PSII reaction centers. Plant Physiol Biochem 84:10-21 (2014). Read more (PubMed: 25240106) »
  • Chen S  et al. Blocking the QB -binding site of photosystem II by tenuazonic acid, a non-host-specific toxin of Alternaria alternata, activates singlet oxygen-mediated and EXECUTER-dependent signalling in Arabidopsis. Plant Cell Environ : (2014). Read more (PubMed: 25292361) »
  • Kostecki M  et al. Biosynthesis and preparation of fiveAlternaria metabolites. Mycotoxin Res 7:3-7 (1991). Read more (PubMed: 23605547) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab144809.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up