Terbinafine hydrochloride, Antifungal and antimycotic (ab141975)

Overview

  • Product name

    Terbinafine hydrochloride, Antifungal and antimycotic
  • Description

    Antifungal and antimycotic
  • Biological description

    Inhibits squalene epoxidase to prevent biosynthesis of ergosterol and squalene monooxygenase. Shows antifungal and antimycotic activity. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    78628-80-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride
  • Molecular weight

    327.90
  • Molecular formula

    C21H25N.HCl
  • PubChem identifier

    5282481
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Zhang JP  et al. Ethosomes, binary ethosomes and transfersomes of terbinafine hydrochloride: a comparative study. Arch Pharm Res 35:109-17 (2012). Read more (PubMed: 22297749) »
  • Sachdeva V  et al. Transdermal iontophoretic delivery of terbinafine hydrochloride: quantitation of drug levels in stratum corneum and underlying skin. Int J Pharm 388:24-31 (2010). Read more (PubMed: 20025950) »
  • Sachdeva V  et al. Iontophoresis mediated in vivo intradermal delivery of terbinafine hydrochloride. Int J Pharm 393:112-8 (2010). Read more (PubMed: 20412843) »

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