Overview

  • Product name

    Tertiapin LQ, Kir1.1 channels blocker
  • Description

    Potent, selective blocker of Kir1.1 channels. Tertiapin Q (ab120432) derivative.
  • Biological description

    Tertiapin Q (ab120432) derivative. Potent, selective blocker of Kir1.1 channels. Shows greater than >250-fold selectivity for Kir1.1 over Kir3.1/3.4 (Kd values are 1.3 and 274 nM at Kir1.1 and Kir3.1/3.4, respectively). Displays greater selectivity at Kir1.1 than Tertiapin Q (ab120432).
  • Purity

    > 95%
  • General notes

    Sold under license granted by the University of Pennsylvania.
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Ramu Y  et al. Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K+ channels. Proc Natl Acad Sci U S A 105:10774-8 (2008). Read more (PubMed: 18669667) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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