Overview

  • Product name

  • Description

    Rabbit polyclonal to TESK2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IP, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to Human TESK2 (internal sequence) conjugated to keyhole limpet haemocyanin.
    Database link: Q96S53

  • Positive control

    • IHC-P: Human testis tissue. WB: Raji, hepG2 and NIH/3T3 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab230644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/10 - 1/100.
IHC-P 1/100.
WB 1/500 - 1/1000. Predicted molecular weight: 64 kDa.

Target

  • Function

    Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
  • Tissue specificity

    Predominantly expressed in testis and prostate. Found predominantly in non-germinal Sertoli cells.
  • Sequence similarities

    Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Dual specificity testis specific protein kinase 2 antibody
    • Dual specificity testis-specific protein kinase 2 antibody
    • MGC29168 antibody
    • OTTHUMP00000009093 antibody
    • RP23-109A3.2 antibody
    • Tesk2 antibody
    • TESK2_HUMAN antibody
    • Testicular protein kinase 2 antibody
    • Testis specific kinase 2 antibody
    see all

Images

  • All lanes : Anti-TESK2 antibody (ab230644) at 1/500 dilution

    Lane 1 : Raji (human Burkitt's lymphoma cell line) whole cell lysate
    Lane 2 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate
    Lane 3 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate

    Predicted band size: 64 kDa

  • Formalin-fixed, paraffin-embedded human testis tissue stained for TESK2 using ab230644 at 1/100 dilution in immunohistochemical analysis.

References

ab230644 has not yet been referenced specifically in any publications.

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