Key features and details
- Rabbit polyclonal to Tetanus Toxin
- Suitable for: WB, ELISA
- Isotype: IgG
Product nameAnti-Tetanus Toxin antibody
DescriptionRabbit polyclonal to Tetanus Toxin
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Other species
Tetanus toxoid (formaldehyde inactivated tetanus toxin).
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.098% Sodium azide
Constituent: Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab53829 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent dilution. Predicted molecular weight: 150 kDa.|
|ELISA||Use at an assay dependent dilution.|
RelevanceTetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.
- Tentoxylysin antibody
- Tetanus toxin chain H antibody
- Tetanus toxin chain L antibody
ab53829 has not yet been referenced specifically in any publications.