Key features and details
- Mouse monoclonal [TH-11] to Tetanus Toxin
- Suitable for: WB
- Isotype: IgG1
Product nameAnti-Tetanus Toxin antibody [TH-11]
See all Tetanus Toxin primary antibodies
DescriptionMouse monoclonal [TH-11] to Tetanus Toxin
Tested applicationsSuitable for: WBmore details
Tissue, cells or virus corresponding to Tetanus Toxin. Clostridium tetani Harvard vaccine strain
Database link: P04958
- WB:Tetanus Toxin.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage bufferpH: 5
Constituents: 50% Glycerol (glycerin, glycerine), 50% PBS
Concentration information loading...
PurityProtein G purified
Light chain typekappa
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab278064 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
RelevanceTetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.
- Tentoxylysin antibody
- Tetanus toxin chain H antibody
- Tetanus toxin chain L antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab278064 has not yet been referenced specifically in any publications.