Key features and details
- Potent, reversible VMAT2 inhibitor
- CAS Number: 58-46-8
- Form / State: Solid
- Source: Synthetic
Product nameTetrabenazine, VMAT2 inhibitor
DescriptionPotent, reversible VMAT2 inhibitor
Biological descriptionPotent, reversible VMAT2 inhibitor (IC50 = 3.2 nM, Ki = 100 nM). Depletes monoamines stores and decreases uptake into synaptic vesicles. Shows antihyperkinetic effects in vivo. Orally active.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146166 has not yet been referenced specifically in any publications.