Overview

  • Product name

    Tetracycline hydrochloride, Broad spectrum antibiotic
  • Description

    Broad spectrum antibiotic
  • Biological description

    Broad spectrum antibiotic, displays bacteriostatic activity. Protein synthesis inhibitor, binds to the 30S ribosomal subunit. Antiapoptotic and anti-inflammatory effects. Active in vivo.
  • Purity

    > 96%
  • CAS Number

    64-75-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride
  • Molecular weight

    480.90
  • Molecular formula

    C22H24N2O8.HCl
  • PubChem identifier

    54683010
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.NC(=O)C1=C(O)[C@@H](N(C)C)[C@@H]2C[C@H]4C(=C(O)[C@]2(O)C1=O)C(=O)c3c(O)cccc3[C@@]4(C)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Bastos LF  et al. Tetracyclines and pain. Naunyn Schmiedebergs Arch Pharmacol 385:225-41 (2012). Read more (PubMed: 22282331) »
  • Wang DD  et al. Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo. Epilepsy Behav 24:314-8 (2012). Read more (PubMed: 22579030) »
  • Chi Z  et al. Binding of tetracycline and chlortetracycline to the enzyme trypsin: spectroscopic and molecular modeling investigations. PLoS One 6:e28361 (2011). Read more (PubMed: 22205948) »

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