Tetrahydropapaverine hydrochloride, salsolinol hydrochloride derivative (ab143155)

Overview

  • Product name

    Tetrahydropapaverine hydrochloride, salsolinol hydrochloride derivative
  • Description

    Salsolinol hydrochloride derivative
  • Biological description

    Salsolinol hydrochloride (ab120603) derivative. Shows selective dopaminergic neurotoxic effects.
  • CAS Number

    6429-04-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
  • Molecular weight

    379.88
  • Molecular formula

    C20H25NO4.HCl
  • PubChem identifier

    22944
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 10 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)OC)OC.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Dang TT & Facchini PJ Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy. Plant Physiol 159:618-31 (2012). Read more (PubMed: 22535422) »
  • Storch A  et al. Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter. Biochem Pharmacol 63:909-20 (2002). Read more (PubMed: 11911843) »
  • Goto K  et al. Neurotoxic effects of papaverine, tetrahydropapaverine and dimethoxyphenylethylamine on dopaminergic neurons in ventral mesencephalic-striatal co-culture. Brain Res 754:260-8 (1997). Read more (PubMed: 9134983) »

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