Tetramethylrhodamine-6-maleimide, Fluorescent reagent (ab145471)

Overview

  • Product name

    Tetramethylrhodamine-6-maleimide, Fluorescent reagent
  • Description

    Fluorescent reagent with high selectivity.
  • Alternative names

    • 6-TAMRA Maleimide
    • TMR6M
    • TMRM
  • Biological description

    Fluorescent reagent used for thiol modifications of peptides, nucleotides, nucleic acids and proteins.

  • Purity

    > 97%
  • CAS Number

    174568-68-4
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    543nm
  • Emission

    575nm
  • Molecular weight

    481.50
  • Molecular formula

    C28H23N3O5
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Egenberger B  et al. A substrate binding hinge domain is critical for transport-related structural changes of organic cation transporter 1. J Biol Chem 287:31561-73 (2012). Read more (PubMed: 22810231) »
  • Muroi Y  et al. Distinct structural changes in the GABAA receptor elicited by pentobarbital and GABA. Biophys J 96:499-509 (2009). Read more (PubMed: 19167300) »
  • Geibel S  et al. Conformational dynamics of the Na+/K+-ATPase probed by voltage clamp fluorometry. Proc Natl Acad Sci U S A 100:964-9 (2003). Read more (PubMed: 12552111) »
  • Meinild AK  et al. Fluorescence studies of ligand-induced conformational changes of the Na(+)/glucose cotransporter. Biochemistry 41:1250-8 (2002). Read more (PubMed: 11802724) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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