Key features and details
- Rabbit polyclonal to TFB1M
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TFB1M antibody
See all TFB1M primary antibodies
DescriptionRabbit polyclonal to TFB1M
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Recombinant fragment within Human TFB1M aa 1-214. The exact sequence is proprietary.
Database link: Q8WVM0
- 293T, A431, HeLa or HepG2 lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
Our Abpromise guarantee covers the use of ab184151 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 39 kDa.|
FunctionS-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.
Tissue specificityUbiquitously expressed.
Involvement in diseaseNote=Variations in TFB1M may influence the clinical expression of aminoglycoside-induced deafness caused by the A1555G mutation in the mitochondrial 12S rRNA.
Sequence similaritiesBelongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
- Information by UniProt
- N'-adenosyl(rRNA) dimethyltransferase 1 antibody
- CGI75 antibody
- Dimethyladenosine transferase 1, mitochondrial antibody
ab184151 has not yet been referenced specifically in any publications.