Overview

  • Product name

  • Description

    Rabbit polyclonal to TFF2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, Sandwich ELISAmore details
  • Species reactivity

    Reacts with: Human, Recombinant fragment
  • Immunogen

    Synthetic peptide corresponding to Human TFF2 aa 24-129.
    Sequence:

    EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY

  • General notes

     This product was previously labelled as Spasmolytic Polypeptide

     

Properties

  • Form

    Lyophilised:Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    pH: 7.20
    Constituent: 100% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab131147 is produced from highly pure recombinant Human TFF2 and purified by affinity chromatography employing an immobilized Human TFF2 matrix
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab131147 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 0.25 µg/ml.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 14 kDa.

The detection limit for recombinant Human TFF2 is 1.5 - 3.0 ng/lane, under either reducing or non- reducing conditions.

Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml.

Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human TFF2.

Target

  • Function

    Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.
  • Tissue specificity

    Stomach.
  • Sequence similarities

    Contains 2 P-type (trefoil) domains.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • SML 1 antibody
    • SML1 antibody
    • SP antibody
    • Spasmolysin antibody
    • Spasmolytic polypeptide antibody
    • spasmolytic protein 1 antibody
    • TFF 2 antibody
    • TFF2 antibody
    • TFF2_HUMAN antibody
    • trefoil factor 2 (spasmolytic protein 1) antibody
    • Trefoil factor 2 antibody
    • Trefoil factor 2 precursor antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human normal gastric mucosa, staining TFF2 with ab131147 at 0.25 &microg/ml. Staining was detected using DAB.

References

ab131147 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab131147.
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