Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
Constituents: 50% Glycerol, PBS, pH 7.5
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab48648 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|RIA||Use at an assay dependent concentration.|
|IP||Use at an assay dependent concentration.|
|WB||Use at an assay dependent concentration. Predicted molecular weight: 35 kDa.|
|ELISA||Use at an assay dependent concentration.|
FunctionInhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Tissue specificityMostly in endothelial cells.
Sequence similaritiesContains 3 BPTI/Kunitz inhibitor domains.
DomainThis inhibitor contains three inhibitory domains. The first domain interacts with VIIa and TF, the second one with Xa.
- Information by UniProt
- Anti convertin antibody
- EPI antibody
- Extrinsic pathway inhibitor antibody
ab48648 has not yet been referenced specifically in any publications.