Overview

  • Product name

  • Description

    Goat polyclonal to TG6
  • Host species

    Goat
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse, Cow, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to Mouse TG6 aa 311-323 (internal sequence) (Cysteine residue).
    Sequence:

    DKYVDSYGRTLED


    Database link: NP_808394.1

  • Positive control

    • Rat lung tissue lysate.
  • General notes

    Previously labelled as Transglutaminase 6. 

Properties

Applications

Our Abpromise guarantee covers the use of ab126858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 79 kDa).

Target

  • Function

    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
  • Involvement in disease

    Defects in TGM6 are the cause of spinocerebellar ataxia type 35 (SCA35) [MIM:613908]. A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA35 patients commonly show upper limb involvement and torticollis. There is no cognitive impairment.
  • Sequence similarities

    Belongs to the transglutaminase superfamily. Transglutaminase family.
  • Information by UniProt
  • Database links

  • Alternative names

    • Protein-glutamine gamma-glutamyltransferase 6 antibody
    • TG6 antibody
    • TGase Y antibody
    • TGase-3-like antibody
    • TGase-6 antibody
    • TGM3L_HUMAN antibody
    • TGM6 antibody
    • TGY antibody
    • Transglutaminase 6 antibody
    • Transglutaminase Y antibody
    • Transglutaminase-3-like antibody
    • Transglutaminase-6 antibody
    see all

Images

  • Anti-TG6 antibody (ab126858) at 2 µg/ml (for one hour) + Rat lung tissue lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 79 kDa

References

ab126858 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab126858.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up