Overview

  • Product name

    Anti-TG6 antibody [EPR10308] - BSA and Azide free
    See all TG6 primary antibodies
  • Description

    Rabbit monoclonal [EPR10308] to TG6 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, Flow Cyt, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human TG6 aa 1-100. The exact sequence is proprietary.
    Database link: O95932

  • General notes

    Ab250287 is the carrier-free version of ab180959. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab250287 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab250287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Flow Cyt Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Detects a band of approximately 79 kDa (predicted molecular weight: 79 kDa).

Target

  • Function

    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
  • Involvement in disease

    Defects in TGM6 are the cause of spinocerebellar ataxia type 35 (SCA35) [MIM:613908]. A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA35 patients commonly show upper limb involvement and torticollis. There is no cognitive impairment.
  • Sequence similarities

    Belongs to the transglutaminase superfamily. Transglutaminase family.
  • Information by UniProt
  • Database links

  • Alternative names

    • Protein-glutamine gamma-glutamyltransferase 6 antibody
    • TG6 antibody
    • TGase Y antibody
    • TGase-3-like antibody
    • TGase-6 antibody
    • TGM3L_HUMAN antibody
    • TGM6 antibody
    • TGY antibody
    • Transglutaminase 6 antibody
    • Transglutaminase Y antibody
    • Transglutaminase-3-like antibody
    • Transglutaminase-6 antibody
    see all

References

ab250287 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab250287.
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