Anti-TGF beta 2 antibody (ab167655)

Submit a review Submit a question References (3)
Western blot - Anti-TGF beta 2 antibody (ab167655)

    Key features and details

    • Mouse polyclonal to TGF beta 2
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-TGF beta 2 antibody
      See all TGF beta 2 primary antibodies

    • Description

      Mouse polyclonal to TGF beta 2

    • Host species

      Mouse

    • Tested applications

      Suitable for: WBmore details

    • Species reactivity

      Reacts with: Human
      Predicted to work with: Rabbit, Horse, Cow, Dog, Chimpanzee, Rhesus monkey

    • Immunogen

      Recombinant full length protein, corresponding to amino acids 1-414 of Human TGF beta 2 (AAH99635.1).

      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • Positive control

      • TGF beta 2 transfected 293T cell lysate

    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab167655 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB
    Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa.
    Notes
    WB
    Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa.

    Target

    • Function

      TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.

    • Involvement in disease

      A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
      Loeys-Dietz syndrome 4
      Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features.

    • Sequence similarities

      Belongs to the TGF-beta family.

    • Post-translational
      modifications

      The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive.

    • Cellular localization

      Secreted.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • BSC-1 cell growth inhibitor antibody
      • BSC1 cell growth inhibitor antibody
      • Cetermin antibody
      • G-TSF antibody
      • Glioblastoma-derived T-cell suppressor factor antibody
      • GTSF antibody
      • LAP antibody
      • Latency-associated peptide antibody
      • MGC116892 antibody
      • MGF antibody
      • Milk growth factor antibody
      • Polyergin antibody
      • TGF-beta-2 antibody
      • TGF-beta2 antibody
      • TGFB2 antibody
      • TGFB2_HUMAN antibody
      • Transforming growth factor beta 2 antibody
      see all

    Images

    • Western blot - Anti-TGF beta 2 antibody (ab167655)
      Western blot - Anti-TGF beta 2 antibody (ab167655)
      All lanes : Anti-TGF beta 2 antibody (ab167655) at 1 µg/ml

      Lane 1 : TGF beta 2 transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 15 µl per lane.

      Secondary
      All lanes : Goat Anti-Mouse IgG HRP at 1/2500 dilution

      Predicted band size: 48 kDa

    References (3)

    Publishing research using ab167655? Please let us know so that we can cite the reference in this datasheet.

    ab167655 has been referenced in 3 publications.

    • Song L  et al. Phytosterol esters attenuate hepatic steatosis in rats with non-alcoholic fatty liver disease rats fed a high-fat diet. Sci Rep 7:41604 (2017). WB ; Rat . PubMed: 28169366
    • Zhuang R  et al. CR6-interacting factor 1 inhibits invasiveness by suppressing TGF-ß-mediated epithelial-mesenchymal transition in hepatocellular carcinoma. Oncotarget 8:94759-94768 (2017). PubMed: 29212264
    • Liu Y  et al. RUNX3 modulates hypoxia-induced endothelial-to-mesenchymal transition of human cardiac microvascular endothelial cells. Int J Mol Med 40:65-74 (2017). PubMed: 28534977

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab167655.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com