Key features and details
- Rabbit polyclonal to TGF beta 2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TGF beta 2 antibody
See all TGF beta 2 primary antibodies
DescriptionRabbit polyclonal to TGF beta 2
Specificityab81076 antibody reacts with the precursor and mature form of TGF beta 2 and to a lesser extent TGF beta 3, but does not cross react with TGF beta 1.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide within Human TGF beta 2 aa 350 to the C-terminus (internal sequence). The exact sequence is proprietary.
Database link: P61812
This product is FOR RESEARCH USE ONLY. For commercial use, please contact email@example.com.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab81076 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
1/100 for 30 min at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol, by boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
FunctionTGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.
Involvement in diseaseA chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
Loeys-Dietz syndrome 4
Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features.
Sequence similaritiesBelongs to the TGF-beta family.
modificationsThe precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive.
- Information by UniProt
- BSC-1 cell growth inhibitor antibody
- BSC1 cell growth inhibitor antibody
- Cetermin antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab81076 has not yet been referenced specifically in any publications.