Overview

  • Product name

  • Description

    Rabbit polyclonal to TGF beta 3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Pig, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human TGF beta 3 (internal sequence). The exact sequence is proprietary.
    Database link: P10600

  • Positive control

    • WB: TGF beta 3 transfected HEK-293T whole cell extract. IHC-P: Mouse lung and kidney tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab227711 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000 - 1/20000. Predicted molecular weight: 47 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Involved in embryogenesis and cell differentiation.
  • Involvement in disease

    Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
  • Sequence similarities

    Belongs to the TGF-beta family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • ARVD antibody
    • ARVD1 antibody
    • FLJ16571 antibody
    • LDS5 antibody
    • MGC105479 antibody
    • MGC118722 antibody
    • prepro-transforming growth factor beta-3 antibody
    • RNHF antibody
    • TGF beta 3 antibody
    • TGF beta3 antibody
    • TGF-beta-3 antibody
    • TGFB 3 antibody
    • Tgfb3 antibody
    • TGFB3_HUMAN antibody
    • transforming growth factor beta 3 antibody
    • Transforming growth factor beta-3 antibody
    see all

Images

  • All lanes : Anti-TGF beta 3 antibody (ab227711) at 1/20000 dilution

    Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extract
    Lane 2 : TGF beta 3 transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extract

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 47 kDa



    12 % SDS-PAGE gel.

  • Paraffin-embedded mouse kidney tissue stained for TGF beta 3 with ab227711 at 1/500 dilution in immunohistochemical analysis.

  • Paraffin-embedded mouse lung tissue stained for TGF beta 3 with ab227711 at 1/500 dilution in immunohistochemical analysis.

References

ab227711 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab227711.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up