Key features and details
- Rabbit polyclonal to TGF beta Receptor III/TGFBR3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TGF beta Receptor III/TGFBR3 antibody
See all TGF beta Receptor III/TGFBR3 primary antibodies
DescriptionRabbit polyclonal to TGF beta Receptor III/TGFBR3
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Pig
Recombinant fragment corresponding to Human TGF beta Receptor III/TGFBR3 aa 88-274.
- NT2D1, IMR32, U87MG and MCF7 cell lysates
This product was previously labelled as TGF beta Receptor III
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab97459 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 93 kDa.|
FunctionBinds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Sequence similaritiesContains 1 ZP domain.
modificationsExtensively modified by glycosaminoglycan groups (GAG).
Cellular localizationSecreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
- Information by UniProt
- Beta glycan antibody
- Betaglycan antibody
- Betaglycan proteoglycan antibody
ab97459 has been referenced in 3 publications.
- Yin Z et al. Macrophage-derived exosomal microRNA-501-3p promotes progression of pancreatic ductal adenocarcinoma through the TGFBR3-mediated TGF-ß signaling pathway. J Exp Clin Cancer Res 38:310 (2019). PubMed: 31307515
- Zakrzewski PK et al. Significance of TGFBR3 allelic loss in the deregulation of TGFß signaling in primary human endometrial carcinomas. Oncol Rep 35:932-8 (2016). PubMed: 26548418
- Priyadarsini S et al. Keratoconus in vitro and the key players of the TGF-ß pathway. Mol Vis 21:577-88 (2015). WB . PubMed: 26015770