Overview

  • Product name

    Anti-TGF beta Receptor III/TGFBR3 antibody
    See all TGF beta Receptor III/TGFBR3 primary antibodies
  • Description

    Rabbit polyclonal to TGF beta Receptor III/TGFBR3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Pig
  • Immunogen

    Recombinant fragment corresponding to Human TGF beta Receptor III/TGFBR3 aa 88-274.

  • Positive control

    • NT2D1, IMR32, U87MG and MCF7 cell lysates
  • General notes

     This product was previously labelled as TGF beta Receptor III

     

     

Properties

Applications

Our Abpromise guarantee covers the use of ab97459 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 93 kDa.

Target

  • Function

    Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
  • Sequence similarities

    Contains 1 ZP domain.
  • Post-translational
    modifications

    Extensively modified by glycosaminoglycan groups (GAG).
  • Cellular localization

    Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
  • Information by UniProt
  • Database links

  • Alternative names

    • Beta glycan antibody
    • Betaglycan antibody
    • Betaglycan proteoglycan antibody
    • BGCAN antibody
    • TGBR3_HUMAN antibody
    • TGF beta receptor type 3 antibody
    • TGF beta receptor type III antibody
    • TGF-beta receptor type 3 antibody
    • TGF-beta receptor type III antibody
    • TGFB R3 antibody
    • TGFBR 3 antibody
    • TGFBR3 antibody
    • TGFR 3 antibody
    • TGFR-3 antibody
    • TGFR3 antibody
    • Transforming growth factor beta receptor III antibody
    • Transforming growth factor beta receptor III betaglycan 300kDa antibody
    • Transforming growth factor beta receptor type 3 antibody
    see all

Images

  • Anti-TGF beta Receptor III/TGFBR3 antibody (ab97459) at 1/1000 dilution + IMR32 whole cell lysate at 30 µg

    Predicted band size: 93 kDa



    7.5% SDS PAGE

References

This product has been referenced in:

  • Yin Z  et al. Macrophage-derived exosomal microRNA-501-3p promotes progression of pancreatic ductal adenocarcinoma through the TGFBR3-mediated TGF-ß signaling pathway. J Exp Clin Cancer Res 38:310 (2019). Read more (PubMed: 31307515) »
  • Priyadarsini S  et al. Keratoconus in vitro and the key players of the TGF-ß pathway. Mol Vis 21:577-88 (2015). WB . Read more (PubMed: 26015770) »
See all 2 Publications for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Application
Western blot
Sample
Rat Cell lysate - whole cell (MCF-7, Rat brain E19, Cortical neurons DIV6/12)
Gel Running Conditions
Reduced Denaturing (10% gel)
Loading amount
40 µg
Specification
MCF-7, Rat brain E19, Cortical neurons DIV6/12
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 24°C

Abcam user community

Verified customer

Submitted Jun 15 2016

Answer

Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products.
I am sorry these 3 products did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued free of charge replacements with the order number xxx for ab50884 and ab78421, and the order number xxx for ab118402 (backordered). The estimated delivery date for the latter product is xxx. I hope this is OK.
To check the status of the order please contact our Customer Service team and reference this number.
Please note that this free of charge replacement vial is also covered by our Abpromise guarantee. Should you still be experiencing difficulties, or if you have any further questions, please do not hesitate to let us know.
I wish you the best of luck with your research.

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