Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
PurityProtein G purified
Purification notesFiltered through a 0.22 µm membrane.
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
Our Abpromise guarantee covers the use of ab50884 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent dilution. Predicted molecular weight: 45 kDa.|
|Dot blot||Use at an assay dependent dilution.|
FunctionBinds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities.
Involvement in diseaseHoloprosencephaly 4
Sequence similaritiesBelongs to the TALE/TGIF homeobox family.
Contains 1 homeobox DNA-binding domain.
- Information by UniProt
- 5' TG 3' interacting factor antibody
- 5''-TG-3''-interacting factor 1 antibody
- Homeobox protein TGIF antibody
Anti-TGIF antibody [946C1a] (ab50884) + immunizing peptide
Predicted band size: 45 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted?
ab50884 has not yet been referenced specifically in any publications.