Anti-TGIF2 antibody (ab222131)
Key features and details
- Rabbit polyclonal to TGIF2
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TGIF2 antibody -
Description
Rabbit polyclonal to TGIF2 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment corresponding to Human TGIF2 aa 100-200.
Database link: Q9GZN2 -
Positive control
- ICC/IF: Caco-2 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab222131 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100. |
Notes |
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. Fixation/Permeabilization: PFA/Triton X-100. |
Target
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Function
Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins. -
Tissue specificity
Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate. -
Sequence similarities
Belongs to the TALE/TGIF homeobox family.
Contains 1 homeobox DNA-binding domain. -
Post-translational
modificationsThe C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway. -
Cellular localization
Nucleus. Excluded from nucleoli. - Information by UniProt
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Database links
- Entrez Gene: 60436 Human
- Entrez Gene: 228839 Mouse
- Entrez Gene: 499929 Rat
- Omim: 607294 Human
- SwissProt: Q9GZN2 Human
- SwissProt: Q8C0Y1 Mouse
- Unigene: 632264 Human
- Unigene: 315625 Mouse
see all -
Alternative names
- 5' TG 3' interacting factor 2 antibody
- 5''-TG-3''-interacting factor 2 antibody
- Homeobox protein TGIF2 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab222131 has not yet been referenced specifically in any publications.