Key features and details
- Rabbit polyclonal to TGIF2
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TGIF2 antibody
See all TGIF2 primary antibodies
DescriptionRabbit polyclonal to TGIF2
Tested applicationsSuitable for: ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
- ICC/IF: Caco-2 cells.
Previously labelled as TGF beta induced factor 2.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab222131 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100.
FunctionTranscriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
Tissue specificityWidely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.
Sequence similaritiesBelongs to the TALE/TGIF homeobox family.
Contains 1 homeobox DNA-binding domain.
modificationsThe C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway.
Cellular localizationNucleus. Excluded from nucleoli.
- Information by UniProt
- 5' TG 3' interacting factor 2 antibody
- 5''-TG-3''-interacting factor 2 antibody
- Homeobox protein TGIF2 antibody
ab222131 has not yet been referenced specifically in any publications.