Overview

  • Product name
  • Description
    Chicken polyclonal to TGIF2
  • Host species
    Chicken
  • Specificity
    This antibody recognises TGIF2.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length protein corresponding to Human TGIF2.

  • General notes

    Previously labelled as TGF beta induced factor 2. 

Properties

Applications

Our Abpromise guarantee covers the use of ab26199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 26 kDa.

Target

  • Function
    Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
  • Tissue specificity
    Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.
  • Sequence similarities
    Belongs to the TALE/TGIF homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Post-translational
    modifications
    The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway.
  • Cellular localization
    Nucleus. Excluded from nucleoli.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5' TG 3' interacting factor 2 antibody
    • 5''-TG-3''-interacting factor 2 antibody
    • Homeobox protein TGIF2 antibody
    • TGF (beta) induced transcription factor 2 antibody
    • TGF beta induced factor 2 antibody
    • TGF-beta-induced transcription factor 2 antibody
    • TGFB induced factor 2 antibody
    • TGFB-induced factor 2 antibody
    • Tgif2 antibody
    • TGIF2_HUMAN antibody
    • Transforming growth factor beta induced factor 2 antibody
    see all

Images

  • Anti-TGIF2 antibody (ab26199) at 1/2000 dilution + E coli derived fusion protein (0.5ug)

    Secondary
    Goat anti IgY HRP at 1/1000 dilution

    Predicted band size: 26 kDa
    Observed band size: >75 kDa
    why is the actual band size different from the predicted?



    The arrow next to the image points to the TGIF2 fusion protein. The actual band size may be greater than the predicted one because it is an E coli-derived fusion protein.

    Colorimetric method used for signal development.

References

ab26199 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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